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CD86 anticorps

CD86 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 1B3 unconjugated
N° du produit ABIN969029
  • Antigène Voir toutes CD86 Anticorps
    CD86
    Reactivité
    • 148
    • 127
    • 54
    • 20
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    • 7
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    • 2
    Humain
    Hôte
    • 82
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    Souris
    Clonalité
    • 176
    • 60
    • 1
    Monoclonal
    Conjugué
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    Cet anticorp CD86 est non-conjugé
    Application
    • 163
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    Western Blotting (WB), ELISA
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human CD86 expressed in E. coli.
    Clone
    1B3
    Isotype
    IgG1
    Top Product
    Discover our top product CD86 Anticorps primaire
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Kim, Lee, Kim, Jee, Kim, Park, Min, Park: "Allelic variants of CD40 and CD40L genes interact to promote antibiotic-induced cutaneous allergic reactions." dans: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, Vol. 39, Issue 12, pp. 1852-6, (2010) (PubMed).

    Carreño, Pacheco, Gutierrez, Jacobelli, Kalergis: "Disease activity in systemic lupus erythematosus is associated with an altered expression of low-affinity Fc gamma receptors and costimulatory molecules on dendritic cells." dans: Immunology, Vol. 128, Issue 3, pp. 334-41, (2010) (PubMed).

    Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." dans: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).

  • Antigène
    CD86
    Autre désignation
    CD86 (CD86 Produits)
    Synonymes
    anticorps B7-2, anticorps B7.2, anticorps B70, anticorps CD28LG2, anticorps LAB72, anticorps B7, anticorps CLS1, anticorps Cd28l2, anticorps ETC-1, anticorps Ly-58, anticorps Ly58, anticorps MB7, anticorps MB7-2, anticorps TS/A-2, anticorps CD86 molecule, anticorps CD86 antigen, anticorps integrin subunit alpha 2b, anticorps CD86, anticorps Cd86, anticorps Itga2b
    Sujet

    Description: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.Tissue specificity: Expressed by activated B-lymphocytes and monocytes.

    Aliases: B70, B7-2, LAB72, CD28LG2, MGC34413, CD86

    Poids moléculaire
    52 kDa
    ID gène
    942
    HGNC
    942
    Pathways
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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