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ELK1 anticorps

ELK1 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 7E10D5 unconjugated
N° du produit ABIN969096
  • Antigène Voir toutes ELK1 Anticorps
    ELK1 (ELK1, Member of ETS Oncogene Family (ELK1))
    Reactivité
    • 157
    • 100
    • 92
    • 13
    • 10
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 145
    • 11
    Souris
    Clonalité
    • 134
    • 23
    Monoclonal
    Conjugué
    • 83
    • 9
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    Cet anticorp ELK1 est non-conjugé
    Application
    • 108
    • 56
    • 41
    • 30
    • 27
    • 27
    • 23
    • 17
    • 7
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    purified
    Immunogène
    Purified recombinant fragment of ELK1 expressed in E. coli.
    Clone
    7E10D5
    Isotype
    IgG1
    Top Product
    Discover our top product ELK1 Anticorps primaire
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Hsieh, Wu, Tsai, Huang, Hsieh, Liu: "PKCalpha expression regulated by Elk-1 and MZF-1 in human HCC cells." dans: Biochemical and biophysical research communications, Vol. 339, Issue 1, pp. 217-25, (2005) (PubMed).

  • Antigène
    ELK1 (ELK1, Member of ETS Oncogene Family (ELK1))
    Autre désignation
    ELK1 (ELK1 Produits)
    Synonymes
    anticorps Elk-1, anticorps Xelk, anticorps Xelk-1, anticorps elk-1, anticorps elk1, anticorps ELK1, ETS transcription factor, anticorps ELK1, member of ETS oncogene family, anticorps ETS domain-containing protein Elk-1, anticorps ELK1, member of ETS oncogene family S homeolog, anticorps ELK1, anticorps Elk1, anticorps Tsp_02690, anticorps elk1, anticorps elk1.S
    Sujet

    Description: The transcription factor ELK1 is a family of member of ETS oncogene family and of the ternary complex factor (TCF) subfamily,which is located on chromosome Xp11.2 and stimulates transcription. binds to purine-rich DNA sequences. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. Elk1 is phosphorylated by MAP kinase pathways at a cluster of S/T motifs at its C terminus,It appears to be a direct target of activated MAP kinase. Biochemical studies indicate that Elk1 is a good substrate for MAP kinase, the kinetics of Elk1phosphorylation and activation correlate with MAP kinase activity, and interfering mutants of MAP kinase block Elk1 activation in vivo. More recent studies have shown that Elk1 is also a target of the Stress Activated Kinase SAPK/JNK. Phosphorylation of Elk1 has also been implicated in synaptic plasticity in the adult hippocampus.

    Aliases: ELK1

    ID gène
    2002
    HGNC
    2002
    Pathways
    Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
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