c-FOS anticorps

N° du produit ABIN969150

Détail du produit anti-c-FOS anticorps

Antigène: c-FOS (c-Fos) (c-Fos)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp c-FOS est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Purification: purified

Immunogène: Purified recombinant fragment of human FOS expressed in E. coli.

Clone: 2G2

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Références pour anticorps anti-c-FOS (ABIN969150)

Das, Muniyappa: "c-Jun-NH2 terminal kinase (JNK)-mediates AP-1 activation by thioredoxin: phosphorylation of cJun, JunB, and Fra-1." dans: Molecular and cellular biochemistry, Vol. 337, Issue 1-2, pp. 53-63, (2010) (PubMed).

Wang, Sun, Jiang, Zhang, Wolfl: "FOS proliferating network construction in early colorectal cancer (CRC) based on integrative significant function cluster and inferring analysis." dans: Cancer investigation, Vol. 27, Issue 8, pp. 816-24, (2009) (PubMed).

Détails sur c-FOS

Antigène: c-FOS (c-Fos) (c-Fos)

Autre désignation: FOS (c-Fos Produits)

Synonymes: anticorps AP-1, anticorps C-FOS, anticorps p55, anticorps c-fos, anticorps D12Rfj1, anticorps cFos, anticorps cFOS, anticorps fos, anticorps Fos proto-oncogene, AP-1 transcription factor subunit, anticorps FBJ osteosarcoma oncogene, anticorps proto-oncogene c-Fos-like, anticorps FOS, anticorps Fos, anticorps LOC101078177

Sujet:

Description: The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.

Aliases: p55, AP-1, C-FOS

Poids moléculaire: 40.7 kDa

ID gène: 2353

HGNC: 2353

Pathways: S100 Proteins