GABPA anticorps (AA 120-190)

N° du produit ABIN969163

Détail du produit anti-GABPA anticorps

Antigène: GABPA (GA Binding Protein Transcription Factor, alpha Subunit 60kDa (GABPA))

Épitope: AA 120-190

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GABPA est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Purification: purified

Immunogène: Purified recombinant fragment of human GABPA (aa120-190) expressed in E. coli.

Clone: 8C1B10

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Références pour anticorps anti-GABPA (ABIN969163)

Sawada, Simizu, Suzuki, Sawa, Goto, Hasegawa, Imai, Watanabe, Handa: "Synergistic transcriptional activation by hGABP and select members of the activation transcription factor/cAMP response element-binding protein family." dans: The Journal of biological chemistry, Vol. 274, Issue 50, pp. 35475-82, (2000) (PubMed).

Vogel, Kristie: "The novel coactivator C1 (HCF) coordinates multiprotein enhancer formation and mediates transcription activation by GABP." dans: The EMBO journal, Vol. 19, Issue 4, pp. 683-90, (2000) (PubMed).

Détails sur GABPA

Antigène: GABPA (GA Binding Protein Transcription Factor, alpha Subunit 60kDa (GABPA))

Autre désignation: GABPA (GABPA Produits)

Sujet:

Description: GABPA: GA binding protein transcription factor, alpha subunit 60 kDa. It is one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, it may play a role in the Down Syndrome phenotype.

Aliases: NFT2, NRF2

Poids moléculaire: 51 kDa

ID gène: 2551

HGNC: 2551

Pathways: Myometrial Relaxation and Contraction