MSH6 anticorps
-
- Antigène Voir toutes MSH6 Anticorps
- MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
-
Reactivité
- Humain
-
Hôte
- Souris
-
Clonalité
- Monoclonal
-
Conjugué
- Cet anticorp MSH6 est non-conjugé
-
Application
- Western Blotting (WB), ELISA
- Purification
- purified
- Immunogène
- Purified recombinant fragment of human MSH6 expressed in E. coli.
- Clone
- 5B11
- Isotype
- IgG1
- Top Product
- Discover our top product MSH6 Anticorps primaire
-
-
- Indications d'application
- ELISA: 1:10000, WB: 1:500 - 1:2000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- 4°C, -20°C for long term storage
-
-
Rab39a binds caspase-1 and is required for caspase-1-dependent interleukin-1beta secretion." dans: The Journal of biological chemistry, Vol. 284, Issue 50, pp. 34531-7, (2009) (PubMed).
: "
-
Rab39a binds caspase-1 and is required for caspase-1-dependent interleukin-1beta secretion." dans: The Journal of biological chemistry, Vol. 284, Issue 50, pp. 34531-7, (2009) (PubMed).
-
- Antigène
- MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
- Autre désignation
- MSH6 (MSH6 Produits)
- Synonymes
- anticorps GTBP, anticorps GTMBP, anticorps HNPCC5, anticorps HSAP, anticorps p160, anticorps cb326, anticorps wu:fb36c12, anticorps LOC100227810, anticorps AU044881, anticorps AW550279, anticorps Gtmbp, anticorps mutS homolog 6, anticorps mutS homolog 6 (E. coli), anticorps DNA mismatch repair protein, anticorps MSH6, anticorps msh6, anticorps Msh6
- Sujet
-
Description: This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein of this gene combines with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene have been identified in individuals with hereditary nonpolyposis colon cancer (HNPCC) and endometrial cancer.
Aliases: GTBP, HSAP, HNPCC5
- Poids moléculaire
- 160 kDa
- ID gène
- 2956
- HGNC
- 2956
- Pathways
- Réparation de l'ADN, Chromatin Binding, Production of Molecular Mediator of Immune Response
-