TNNI2 anticorps

N° du produit ABIN969441

Détail du produit anti-TNNI2 anticorps

Antigène: TNNI2 (Fast Skeletal Troponin I (TNNI2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TNNI2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Purification: purified

Immunogène: Purified recombinant fragment of human TNNI2 expressed in E. coli.

Clone: 2F12A11

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Références pour anticorps anti-TNNI2 (ABIN969441)

Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." dans: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).

Moran, Garriock, Miller, Heimark, Gregorio, Krieg: "Expression of the fast twitch troponin complex, fTnT, fTnI and fTnC, in vascular smooth muscle." dans: Cell motility and the cytoskeleton, Vol. 65, Issue 8, pp. 652-61, (2008) (PubMed).

Détails sur TNNI2

Antigène: TNNI2 (Fast Skeletal Troponin I (TNNI2))

Autre désignation: TNNI2 (TNNI2 Produits)

Synonymes: anticorps AMCD2B, anticorps DA2B, anticorps FSSV, anticorps fsTnI, anticorps TnI-F4, anticorps TnI, anticorps TNI, anticorps hm:zehn0173, anticorps tnni2, anticorps tropI-1d, anticorps zgc:86800, anticorps troponin I2, fast skeletal type, anticorps troponin I type 2 (skeletal, fast), anticorps troponin I, fast skeletal muscle-like, anticorps troponin I, skeletal, fast 2, anticorps troponin I type 2a (skeletal, fast), tandem duplicate 4, anticorps TNNI2, anticorps Tnni2, anticorps tnni2a.4

Sujet:

Description: This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene.

Aliases: DA2B, FSSV, fsTnI, AMCD2B

Poids moléculaire: 21 kDa

ID gène: 7136

HGNC: 7136