Fibrinogen anticorps

N° du produit ABIN99207

Détail du produit anti-Fibrinogen anticorps

Antigène: Fibrinogen

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Fibrinogen est non-conjugé

Application: ELISA

Attributs du produit: Concentration Definition: by UV absorbance at 280 nm

Immunogène: Fibrinogen [Human Plasma]
Immunogentype:Native

Isotype: IgG

Information d'application

Indications d'application: Anti-FIBRINOGEN has been assayed against 1.0 µg of Fibrinogen [Human Plasma] in a standard sandwich ELISA using Peroxidase conjugated Affinity Purified anti-Goat IgG [H&L] Rabbit) (ABTS (2,2’-azino-bis-[3-ethylbenthiazoline-6-sulfonic acid]) as a substrate for 30 minutes at room temperature.  A working dilution of 1:10,000 to 1:50,000 of the reconstitution concentration is suggested for this product. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Restore with deionized water (or equivalent)

Concentration: 10.0 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur Fibrinogen

Antigène: Fibrinogen

Abstract: Fibrinogen Produits

Synonymes: anticorps fib2, anticorps MGC53620, anticorps fibrinogen, anticorps sb:cb892, anticorps wu:fa55c12, anticorps wu:fb20e08, anticorps wu:fb59b03, anticorps wu:fi39d04, anticorps zgc:92117, anticorps fibrinogen alpha chain, anticorps fibrinogen gamma chain, anticorps fga, anticorps FGA, anticorps LOC698244, anticorps CpipJ_CPIJ010090, anticorps FGG

Sujet: Fibrinogen (factor I) is a soluble plasma glycoprotein, synthesised by the liver, that is converted by thrombin into fibrin during blood coagulation. This is achieved through processes in the coagulation cascade that activate the zymogen prothrombin to the serine protease thrombin, which is responsible for converting fibrinogen into fibrin. Fibrin is then cross linked by factor XIII to form a clot. FXIIIa stabilizes fibrin further by incorporation of the fibrinolysis inhibitors alpha-2-antiplasmin and TAFI (thrombin activatable fibrinolysis inhibitor, procarboxypeptidase B), and binding to several adhesive proteins of various cells. Both the activation of Factor XIII by thrombin and plasminogen activator (t-PA) are catalyzed by fibrin. Fibrin specifically binds the activated coagulation factors factor Xa and thrombin and entraps them in the network of fibers, thus functioning as a temporary inhibitor of these enzymes, which stay active and can be released during fibrinolysis. Recent research has shown that fibrin plays a key role in the inflammatory response. Anti-Fibrinogen (Human Plasma) is ideal for Serum Protein Component research.
Synonyms: FGA antibody, FGA protein antibody, FGB antibody, FGG antibody, Fib2 antibody, Fibrinogen A alpha polypeptide antibody, Fibrinogen A alpha polypeptide chain antibody, Fibrinogen alpha chain antibody

ID gène: 2243

UniProt: P02671