anti-Humain Caspase 1 anticorps pour Simple Western

Recommended Caspase 1 Antibody (fourni par: Connectez-vous pour afficher )

Antigène
Caspase 1 (CASP1) Anticorps
  • ICE
  • IL1BC
  • P45
  • Il1bc
  • Ice
  • CASP1
  • CG5370
  • DCP-1
  • DCP1
  • Dcp1
  • Dmel\\CG5370
  • ccp1
  • dcp-1
  • dcp1
  • l(2)01862
  • l(2)02132
  • caspase 1
  • caspase 1, apoptosis-related cysteine peptidase
  • caspase 4, apoptosis-related cysteine peptidase
  • Death caspase-1
  • caspase-1
  • caspase
  • caspase recruitment domain-containing protein 16
  • caspase 4
  • CASP1
  • Casp1
  • CASP4
  • Dcp-1
  • Caspase1
  • LOC5564196
  • LOC451519
Reactivité
Humain, Souris, Rat (Rattus)
258
95
74
8
2
2
2
1
1
1
1
1
1
Hôte
Souris
250
36
8
2
Clonalité
Monoclonal
Conjugué
Cet anticorp Caspase 1 est non-conjugé
23
16
8
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Simple Western (SimWes), Western Blotting (WB)
266
160
118
75
32
26
18
15
7
5
3
2
1
Fournisseur
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N° du produit (Fournisseur)
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N° du produit ABIN252521
Produit non disponible pour cette région.
Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
31.444967 ABIN4288024 IHC IHC (p) SimWes WB Mouse IgG1 kappa Connectez-vous pour afficher 14F468 0
1 ABIN4288000 IHC IHC (p) SimWes WB Mouse IgG1 kappa Connectez-vous pour afficher 14F468 0

General

Antigène Caspase 1 (CASP1) Anticorps
Reactivité Humain, Souris, Rat (Rattus)
(258), (95), (74), (8), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Hôte Souris
(250), (36), (8), (2)
Clonalité (Clone)
Monoclonal   ( )
Conjugué Cet anticorp Caspase 1 est non-conjugé
(23), (16), (8), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Simple Western (SimWes), Western Blotting (WB)
(266), (160), (118), (75), (32), (26), (18), (15), (7), (5), (3), (2), (1)
Pubmed 26 références disponible
Fournisseur Connectez-vous pour afficher

Détail du produit anti-Caspase 1 anticorps

Détail du antigène Caspase 1 Information d'application Stockage References for anti-Caspase 1 antibody (ABIN252521) Images
Specificité The antibody will recognize full-length Caspase-1 and cleaved caspase-1 forms that retain amino acids 371-390 of the Caspase-1 protein.
Purification Protein G purified
Immunogène A synthetic peptide corresponding to amino acids 371-390 RKVRFSFEQPDGRAQMPTTE of human caspase-1 was used as immunogen.
Clone 14F468
Isotype IgG1 kappa
Plasmids, Primers & others

Détail du antigène Caspase 1

Détail du produit anti-Caspase 1 anticorps Information d'application Stockage References for anti-Caspase 1 antibody (ABIN252521) Images Haut de la page
Antigène
Autre désignation Caspase-1 (CASP1 Antibody Extrait)
Sujet Gene Symbol: CASP1
Poids moléculaire Theoretical MW: 45 kDa
ID gène 834
UniProt P29466
Pathways Apoptose, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity

Information d'application

Détail du produit anti-Caspase 1 anticorps Détail du antigène Caspase 1 Stockage References for anti-Caspase 1 antibody (ABIN252521) Images Haut de la page
Indications d'application Western Blot 0.5-2 μg/mL, Simple Western 1:50, Immunohistochemistry 1:20-1:1000, Immunohistochemistry-Paraffin 1:10-1:500Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM sodium citrate buffer, pH 6.0 for 10-20 min followed by cooling at RT for 20 min. In Simple Western only 10 - 15 μL of the recommended dilution is used per data point. Separated by Size-Wes, Sally Sue/Peggy Sue. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Commentaires

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only

Stockage

Détail du produit anti-Caspase 1 anticorps Détail du antigène Caspase 1 Information d'application References for anti-Caspase 1 antibody (ABIN252521) Images Haut de la page
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS
Buffer contains: 0.05 % Sodium Azide
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid freeze-thaw cycles
Stock 4 °C,-20 °C
Stockage commentaire Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

References for anti-Caspase 1 antibody (ABIN252521)

Détail du produit anti-Caspase 1 anticorps Détail du antigène Caspase 1 Information d'application Stockage Images Haut de la page
Produit citée dans:

dAdesky, de Rivero Vaccari, Bhattacharya, Schatz, Perez-Pinzon, Bramlett, Raval: "Nicotine Alters Estrogen Receptor-Beta-Regulated Inflammasome Activity and Exacerbates Ischemic Brain Damage in Female Rats." dans: International journal of molecular sciences, Vol. 19, Issue 5, 2018

de Rivero Vaccari, Brand, Adamczak, Lee, Perez-Barcena, Wang, Bullock, Dietrich, Keane: "Exosome-mediated inflammasome signaling after central nervous system injury." dans: Journal of neurochemistry, Vol. 136 Suppl 1, pp. 39-48, 2016 (Échantillon (espèces): Human). Détails: Western Blotting,Immunohistochemistry (Paraffin-embedded Sections)

Lin, Li, Zha, Xu, Pan, Zhao, Ouyang, He: "Gossypol induces pyroptosis in mouse macrophages via a non-canonical inflammasome pathway." dans: Toxicology and applied pharmacology, Vol. 292, pp. 56-64, 2016 (Échantillon (espèces): Rat (Rattus)). Détails: Western Blotting

Lévesque, Paré, Mailhot, Bellver-Landete, Kébir, Lécuyer, Alvarez, Prat, de Rivero Vaccari, Keane, Lacroix: "Myeloid cell transmigration across the CNS vasculature triggers IL-1β-driven neuroinflammation during autoimmune encephalomyelitis in mice." dans: The Journal of experimental medicine, Vol. 213, Issue 6, pp. 929-49, 2016 (Échantillon (espèces): Mouse (Murine)). Détails: Western Blotting

Fernandez, Miller, Krammer, Gopal, Greenbaum, Bhardwaj: "Ion efflux and influenza infection trigger NLRP3 inflammasome signaling in human dendritic cells." dans: Journal of leukocyte biology, Vol. 99, Issue 5, pp. 723-34, 2016 Méthode utilisée: Western Blotting (WB) (Échantillon (espèces): Human).

Rimessi, Bezzerri, Patergnani, Marchi, Cabrini, Pinton: "Mitochondrial Ca2+-dependent NLRP3 activation exacerbates the Pseudomonas aeruginosa-driven inflammatory response in cystic fibrosis." dans: Nature communications, Vol. 6, pp. 6201, 2015 (Échantillon (espèces): Human). Détails: Western Blotting

Queen, Agarwal, Dolores, Stehlik, Satchell: "Mechanisms of inflammasome activation by Vibrio cholerae secreted toxins vary with strain biotype." dans: Infection and immunity, Vol. 83, Issue 6, pp. 2496-506, 2015 (Échantillon (espèces): Human). Détails: Western Blotting

Melehani, James, DuMont, Torres, Duncan: "Staphylococcus aureus Leukocidin A/B (LukAB) Kills Human Monocytes via Host NLRP3 and ASC when Extracellular, but Not Intracellular." dans: PLoS pathogens, Vol. 11, Issue 6, pp. e1004970, 2015 (Échantillon (espèces): Human). Détails: Western Blotting

Paciello, Silipo, Lembo-Fazio, Curcurù, Zumsteg, Noël, Ciancarella, Sturiale, Molinaro, Bernardini: "Intracellular Shigella remodels its LPS to dampen the innate immune recognition and evade inflammasome activation." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 46, pp. E4345-54, 2013 (Échantillon (espèces): Mouse (Murine)). Détails: Western Blotting

Mawhinney, de Rivero Vaccari, Dale, Keane, Bramlett: "Heightened inflammasome activation is linked to age-related cognitive impairment in Fischer 344 rats." dans: BMC neuroscience, Vol. 12, pp. 123, 2012 (Échantillon (espèces): Rat (Rattus)). Détails: Western Blotting

de Rivero Vaccari, Bastien, Yurcisin, Pineau, Dietrich, De Koninck, Keane, Lacroix: "P2X4 receptors influence inflammasome activation after spinal cord injury." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 9, pp. 3058-66, 2012

de Rivero Vaccari, Sawaya, Brand, Nusbaum, Bauman, Bramlett, Dietrich, Keane: "Caspase-1 level is higher in the scalp in androgenetic alopecia." dans: Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], Vol. 38, Issue 7 Pt 1, pp. 1033-9, 2012

Tomura, de Rivero Vaccari, Keane, Bramlett, Dietrich: "Effects of therapeutic hypothermia on inflammasome signaling after traumatic brain injury." dans: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 32, Issue 10, pp. 1939-47, 2012

Taxman, Swanson, Broglie, Wen, Holley-Guthrie, Huang, Callaway, Eitas, Duncan, Ting: "Porphyromonas gingivalis mediates inflammasome repression in polymicrobial cultures through a novel mechanism involving reduced endocytosis." dans: The Journal of biological chemistry, Vol. 287, Issue 39, pp. 32791-9, 2012

Zhang, Ibrahim, de Rivero Vaccari, Lotocki, Aballa, Dietrich, Keane, Lynne, Brackett: "Involvement of the inflammasome in abnormal semen quality of men with spinal cord injury." dans: Fertility and sterility, Vol. 99, Issue 1, pp. 118-24, 2012

Atay, Gercel-Taylor, Taylor: "Human trophoblast-derived exosomal fibronectin induces pro-inflammatory IL-1β production by macrophages." dans: American journal of reproductive immunology (New York, N.Y. : 1989), Vol. 66, Issue 4, pp. 259-69, 2011

Taxman, Holley-Guthrie, Huang, Moore, Bergstralh, Allen, Lei, Gris, Ting: "The NLR adaptor ASC/PYCARD regulates DUSP10, mitogen-activated protein kinase (MAPK), and chemokine induction independent of the inflammasome." dans: The Journal of biological chemistry, Vol. 286, Issue 22, pp. 19605-16, 2011

Nadeau, Filali, Zhang, Kerr, Rivest, Soulet, Iwakura, de Rivero Vaccari, Keane, Lacroix: "Functional recovery after peripheral nerve injury is dependent on the pro-inflammatory cytokines IL-1β and TNF: implications for neuropathic pain." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 35, pp. 12533-42, 2011 (Échantillon (espèces): Mouse (Murine)).

Rawat, Cohen, Ampong, Francia, Henriques-Pons, Hoffman, Nagaraju: "Inflammasome up-regulation and activation in dysferlin-deficient skeletal muscle." dans: The American journal of pathology, Vol. 176, Issue 6, pp. 2891-900, 2010

Banerjee, Datta, Majumder, Mukhopadhyay, Bhattacharyya: "Transcription regulation of caspase-1 by R393 of HIPPI and its molecular partner HIP-1." dans: Nucleic acids research, Vol. 38, Issue 3, pp. 878-92, 2010

Images

Détail du produit anti-Caspase 1 anticorps Détail du antigène Caspase 1 Information d'application Stockage References for anti-Caspase 1 antibody (ABIN252521) Haut de la page
Images (Fournisseur)
Western Blotting (WB) image for anti-Caspase 1 (CASP1) antibody (ABIN252521) Western blot analysis of Caspase-1 in A) HeLa cell lysate at 0.5 ug/ml and B) NIH 3T3...
Immunohistochemistry (IHC) image for anti-Caspase 1 (CASP1) antibody (ABIN252521) Formalin-fixed, paraffin-embedded sections of human colon cancer stained for caspase-...
Immunohistochemistry (IHC) image for anti-Caspase 1 (CASP1) antibody (ABIN252521) anti-Caspase 1 (CASP1) antibody (Image 3)
Western Blotting (WB) image for anti-Caspase 1 (CASP1) antibody (ABIN252521) Western Blot: Caspase-1 Antibody (14F468) [ABIN2525215] - Analysis using Azide and BS...
Simple Western (SimWes) image for anti-Caspase 1 (CASP1) antibody (ABIN252521) Simple Western: Caspase-1 Antibody (14F468) [ABIN2525215] - Simple Western lane view ...
Simple Western (SimWes) image for anti-Caspase 1 (CASP1) antibody (ABIN252521) Simple Western: Caspase-1 Antibody (14F468) [ABIN2525215] - Analysis using Azide and ...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Caspase 1 (CASP1) antibody (ABIN252521) Immunohistochemistry-Paraffin: Caspase-1 Antibody (14F468) [ABIN2525215] - Detection ...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Caspase 1 (CASP1) antibody (ABIN252521) Immunohistochemistry-Paraffin: Caspase-1 Antibody (14F468) [ABIN2525215] - IHC-P dete...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Caspase 1 (CASP1) antibody (ABIN252521) Immunohistochemistry-Paraffin: Caspase-1 Antibody (14F468) [ABIN2525215] - Analysis u...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Caspase 1 (CASP1) antibody (ABIN252521) Immunohistochemistry-Paraffin: Caspase-1 Antibody (14F468) [ABIN2525215] - Analysis u...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Caspase 1 (CASP1) antibody (ABIN252521) Immunohistochemistry-Paraffin: Caspase-1 Antibody (14F468) [ABIN2525215] - Analysis u...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Caspase 1 (CASP1) antibody (ABIN252521) Immunohistochemistry-Paraffin: Caspase-1 Antibody (14F468) [ABIN2525215] - Detection ...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Caspase 1 (CASP1) antibody (ABIN252521) Immunohistochemistry-Paraffin: Caspase-1 Antibody (14F468) [ABIN2525215] - IHC-P dete...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Caspase 1 (CASP1) antibody (ABIN252521) Immunohistochemistry-Paraffin: Caspase-1 Antibody (14F468) [ABIN2525215] - Analysis u...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Caspase 1 (CASP1) antibody (ABIN252521) Immunohistochemistry-Paraffin: Caspase-1 Antibody (14F468) [ABIN2525215] - Analysis u...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Caspase 1 (CASP1) antibody (ABIN252521) Immunohistochemistry-Paraffin: Caspase-1 Antibody (14F468) [ABIN2525215] - Formalin-f...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Caspase 1 (CASP1) antibody (ABIN252521) Immunohistochemistry-Paraffin: Caspase-1 Antibody (14F468) - IHC analysis of a forma...