Caspase 12 Protéines
4 Caspase 12 (Gene/pseudogene) (CASP12) Protéines de 3 fabricants sont disponibles sur www.anticorps-enligne.fr.
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4 Résultats:
Caspase 12 (Gene/pseudogene) (CASP12) (AA 1-341) protein (His tag) Protein
Caspase 12 (Gene/pseudogene) (CASP12) (AA 1-413) protein (His tag,GST tag) Protein
Caspase 12 (Gene/pseudogene) (CASP12) (AA 1-244) protein (His tag,T7 tag) Protein
Caspase 12 (Gene/pseudogene) (CASP12) Protéine Protein
Profil protéine Caspase 12 (CASP12)
Profil protéine
Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for this gene.
Alternative names and synonyms associated with Caspase 12 (CASP12)
- caspase 12 (Casp12) anticorps
- caspase 12 (gene/pseudogene) (CASP12) anticorps
- CASP-12 anticorps
- CASP12P1 anticorps
Protein level used designations for CASP12
CASP-12 , caspase-12 , caspase 12 pseudogene 1 , inactive caspase-12
| GENE ID | SPECIES |
|---|---|
| 12364 | Mus musculus |
| 156117 | Rattus norvegicus |
| 100506742 | Homo sapiens |
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