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anti-Mouse (Murine) KRT18 Anticorps:
anti-Human KRT18 Anticorps:
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Cow (Bovine) Monoclonal KRT18 Primary Antibody pour IHC (fro), IHC (p) - ABIN111183
Bantel, Ruck, Gregor, Schulze-Osthoff: Detection of elevated caspase activation and early apoptosis in liver diseases. dans European journal of cell biology 2001
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Cow (Bovine) Monoclonal KRT18 Primary Antibody pour FACS, IHC (fro) - ABIN111182
Bártek, Vojt?sek, Stasková, Bártková, Kerekés, Rejthar, Kovarík: A series of 14 new monoclonal antibodies to keratins: characterization and value in diagnostic histopathology. dans The Journal of pathology 1991
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Human Monoclonal KRT18 Primary Antibody pour ICC, FACS - ABIN335331
Ivanyi, Groeneveld, Van Doornewaard, Mooi, Hageman: Keratin subtypes in carcinomas of the uterine cervix: implications for histogenesis and differential diagnosis. dans Cancer research 1990
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Human Monoclonal KRT18 Primary Antibody pour ICC, FACS - ABIN335330
Puts, Moesker, Kenemans, Vooijs, Ramaekers: Expression of cytokeratins in early neoplastic epithelial lesions of the uterine cervix. dans International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 1986
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Human Monoclonal KRT18 Primary Antibody pour ICC, FACS - ABIN335341
Bonfrer, Groeneveld, Korse, van Dalen, Oomen, Ivanyi: Monoclonal antibody M3 used in tissue polypeptide-specific antigen assay for the quantification of tissue polypeptide antigen recognizes keratin 18. dans Tumour biology 1994
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Human Monoclonal KRT18 Primary Antibody pour WB - ABIN1882230
Würtz, Grove, Wulff, Kaltoft, Tilsted, Jensen, Hvas, Kristensen: Patients with previous definite stent thrombosis have a reduced antiplatelet effect of aspirin and a larger fraction of immature platelets. dans JACC. Cardiovascular interventions 2010
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Mammalian Monoclonal KRT18 Primary Antibody pour ELISA, FACS - ABIN192045
Cap, Cerman, Nemecek, Marekova, Hana, Frysak: The influence of treatment with somatostatin analogues on morphology, proliferative and apoptotic activity in GH-secreting pituitary adenomas. dans Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2003
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Mammalian Monoclonal KRT18 Primary Antibody pour ELISA, FACS - ABIN94280
Taylor-Papadimitriou, Stampfer, Bartek, Lewis, Boshell, Lane, Leigh: Keratin expression in human mammary epithelial cells cultured from normal and malignant tissue: relation to in vivo phenotypes and influence of medium. dans Journal of cell science 1990
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Human Monoclonal KRT18 Primary Antibody pour ICC, FACS - ABIN94282
Ta: Primary human hepatocytes on biodegradable poly(l-lactic acid) matrices: a promising model for improving transplantation efficiency with tissue engineering. dans Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2011
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Mammalian Monoclonal KRT18 Primary Antibody pour ICC, FACS - ABIN94279
Kovarík, Rejthar, Lauerová, Vojt?sek, Bártková: Monoclonal antibodies against individual cytokeratins in the detection of metastatic spread. dans International journal of cancer. Supplement = Journal international du cancer. Supplement 1989
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K18 deficiency of hepatocytes leads to steatosis, increasing with age, and finally to SH. K18 deficiency and age promote liver tumor development in mice, frequently on the basis of chromosomal instability, resembling human HCC (Montrer FAM126A Anticorps) with stemness features.
K8/K18-dependent PKCdelta (Montrer PKCd Anticorps)- and ASMase (Montrer SMPD1 Anticorps)-mediated modulation of lipid raft size can explain the more prominent FasR-mediated signaling resulting from K8/K18 loss.
autoantibodies were detected in aging K18-null male mice that had a related liver phenotype but normal colon compared with K8-null mice, suggesting that the autoantibodies are linked to liver rather than colonic disease
In human failing myocardium, where TNF-alpha (Montrer TNF Anticorps) expression is upregulated, K8/K18 were also ectopically expressed
The findings demonstrate the near complete loss of K8/K18 with concomitant high levels of vimentin (Montrer VIM Anticorps) in CT26 (Montrer DDX53 Anticorps) cells, a chemically-induced mouse colonic tumor.
in contrast to its importance as luminal cell marker, CK18 is dispensable for the prostate morphogenesis but contributes to adult prostate regeneration
Keratin 18 increases CFTR (Montrer CFTR Anticorps) expression by binding to its C-terminal hydrophobic domain.
Oxidative stress, Nrf2 (Montrer NFE2L2 Anticorps) and keratin 18 up-regulation associate with Mallory-Denk body formation in mouse erythropoietic protoporphyria (Montrer FECH Anticorps)
Keratin 8 (Montrer KRT8 Anticorps) and keratin 18 mice on the same genetic background show similar sensitivity to DDC (Montrer DDC Anticorps) intoxication.
These findings reveal the potential for cytokeratin 18 to be used as a diagnostic marker for early detection of hepatosplenic schistosomiasis.
results show that the caspase digestion-resistant K18 helps to maintain keratin filament organization and delays apoptosis, thereby resulting in protection from liver injury.
K8/K18 variants are overrepresented in Chinese NAFLD (Montrer TSC2 Anticorps) patients and might accelerate liver fat storage through insulin (Montrer INS Anticorps) resistance.
The plasma keratin-18 (K18) values of nonsurviving alcoholic hepatitis (AH) patients were significantly elevated above their surviving counterparts and healthy controls
Evidence suggested that the modification of histone H3 (Montrer HIST3H3 Anticorps) was highly correlated with the modulation of cytokeratin 18 and probably plays an important role in tumorigenesis of hepatocytes
K8/K18 interact with Notch1 (Montrer NOTCH1 Anticorps) and regulate Notch1 (Montrer NOTCH1 Anticorps) signalling activity during differentiation of the colonic epithelium.
FIB (Montrer FBL Anticorps)-4 index and CK-18F have good diagnostic abilities not only for nonalcoholic steatohepatitis (NASH (Montrer SAMSN1 Anticorps)) overall, but also for NASH (Montrer SAMSN1 Anticorps) with mild fibrosis.
In children with nonalcoholic fatty liver disease, CK18 levels were found to be significantly higher in subjects with any fibrosis compared with those without fibrosis (304.6 +/- 124.8 vs 210.4 +/- 70.9, P < 0.001).
CK18 combined with uric acid measurement is a promising non-invasive biomarker for prediction of disease severity in NASH (Montrer SAMSN1 Anticorps) patients
Data show that the filament elongation of both desmin (Montrer DES Anticorps) and keratin K8/K18 proceeds very similar to that of vimentin (Montrer VIM Anticorps).
We present results of a multicentre study measuring UBC (Montrer RPS27A Anticorps)((R)) Rapid Test(test that detects fragments of cytokeratins 8 and 18 in urine) in bladder cancer patients and healthy controls with focus on carcinoma in situ (CIS (Montrer CISH Anticorps)) and high-grade bladder cancer.
Data identify Danio rerio keratins 8/18 as the true orthologs of the human keratin pair 8/18.
krt18 is maternally inherited and its tissue distribution is reported. Its expression is established during early embryogenesis.
Ezrin (Montrer EZR Anticorps) and CK18 are downregulated during implantation in cattle. The expression changes represent a temporal depolarization, which could be important for an establishment of bovine pregnancy.
Results did not support that K8/K18 filaments influence the expression of Fas (Montrer FAS Anticorps) on the surface of luteal cells.
Data indicate that CK18 may be a molecular marker for bovine M cells in follicule-associated epithelium of Peyer's patches.
KRT18 knockdown in preimplantation embryos results in reduced blastocyst formation, but no further morphological aberrations were observed with regard to the biological function of KRT18.
Mechanical injury of vascular smooth muscle up-regulated keratin 18.
KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.
, Endo B
, cytokeratin endo B
, keratin D
, keratin complex 1, acidic, gene 18
, keratin, type I cytoskeletal 18
, cell proliferation-inducing gene 46 protein
, cell proliferation-inducing protein 46
, cytokeratin 18
, dorsal aorta proneprin kinesin-1
, keratin 18
, simple type I keratin
, Keratin, type I cytoskeletal 18
, keratin, type I cytoskeletal 18-like
, keratin 18, type I