Aperçu des produits pour anti-YWHAQ (YWHAQ) Anticorps

Human tyrosine 3-Monooxygenase/tryptophan 5-Monooxygenase Activation Protein, theta Polypeptide (YWHAQ) interaction partners

1. Crystal structures of 14-3-3 chimeras with three different peptides indicate detailed structural information on peptide-14-3-3 interactions.

2. IRSp53 heterodimer with only one subunit is phosphorylated, and each subunit of IRSp53 independently binds one 14-3-3 dimer.

3. Chk1 and 14-3-3 proteins cooperate to inactivate the transcriptional repressor functions of atypical E2F proteins. This mechanism might be of particular importance to cancer cells, since they are exposed frequently to DNA-damaging therapeutic reagents.

4. results suggest that PKC SUMOylation is an important regulator of the 14-3-3 and GluK2a protein complex and may contribute to regulate the decay kinetics of kainate receptor-excitatory postsynaptic currents

5. Results show that 14-3-3zeta promotes cell proliferation, migration and invasion in lung adenocarcinoma. 14-3-3zeta upregulates MUC1 expression through enhancing MUC1/NFkappaB feedback loop. Its high expression is associated with poor survival in lung adenocarcinoma patients.

6. TGFbetaR1 signaling was involved in 14-3-3zeta-mediated cell proliferation and metastasis of lung squamous cell carcinoma cells.

7. Loss of Par3 promotes metastatic behavior in lung adenocarcinoma cells through 14-3-3zeta protein.

8. this study reveals that 14-3-3zeta plays a critical role in Wnt5a/ROR1 signaling, leading to enhanced CLL migration and proliferation.

9. AKT and 14-3-3 proteins down-regulate the activity of several BCR-associated components, including BTK, BLNK and SYK and also inhibit SYK's interaction with Importin 7

10. Our results indicate that TRIM25 is associated with cisplatin resistance and 14-3-3sigma-MDM2-p53 signaling pathway is involved in this process, suggesting targeting TRIM25 may be a potential strategy for the reversal of cisplatin resistance.

11. Up-regulation of 14-3-3zeta in response to pVHL is important for the recruitment of PI3K to the cell membrane and for stabilization of soluble beta-catenin.

12. The 14-3-3 family is dysregulated in schizophrenia, perhaps owing to specific regulatory mechanisms; the expression of the 14-3-3 epsilon, theta and zeta isoforms could be useful indicators of disease severity.

13. High urine 14-3-3 expression is associated with Advanced Stage in Patients with Clear Cell Renal Cell Carcinoma.

14. Levels of 14-3-3 protein predict poorer radiographic outcomes in inflammatory polyarthritis patients.

15. Study shows that 14-3-3 zeta/delta is important in the extracellular vesicles mediated induction of colon malignant phenotype, suggesting its role as a potential target for therapeutic interventions.

16. the effects of cell viability, migration and invasion were mediated in 14-3-3zeta-dependent manner while that of cell apoptosis was mediated in 14-3-3zeta-independent manner.

17. 14-3-3zeta reduces DNA damage by interacting with and stabilizing proliferating cell nuclear antigen

18. phosphorylation of HS1 tyrosines at positions 222, 378 and 397 was required for transendothelial migration of NK cells.

19. Mimitin and 14-3-3 protein zeta/delta are potential markers of paclitaxel resistance and prognostic factors in ovarian cancer.

20. 14-3-3S is an interesting protein biomarker with the potential to further improve the accuracy of differential diagnostic process of hepatocellular tumors.

Mouse (Murine) tyrosine 3-Monooxygenase/tryptophan 5-Monooxygenase Activation Protein, theta Polypeptide (YWHAQ) interaction partners

1. Rod photoreceptors are enriched in YWHAE (14-3-3 epsilon). Immunohistochemistry revealed that 14-3-3 epsilon and 14-3-3 zeta exhibit unique distributions in photoreceptors with 14-3-3 epsilon restricted to the inner segment and 14-3-3 zeta localized to the outer segment.

2. analysis of phosphorylation-dependent interactions of AQP2 with 14-3-3theta; and -zeta

3. Results identify a critical role for 14-3-3tau in promoting breast cancer metastasis, in part through binding to and inhibition of RhoGDIalpha, a negative regulator of Rho GTPases and a metastasis suppressor. [14-3-3tau]

4. Data show that IkappaB kinase (IKK) phosphorylation of the TPL-2 kinase (TPL-2) induces 14-3-3 association with TPL-2, stimulating its MEK kinase activity, which is essential for TPL-2 activation of ERK-1/2.

5. There is a scaffolding role for 14-3-3theta in assisting the delivery of Cx43 and integrin alpha5 to the plasma membrane for the formation of mechanosensitive hemichannels in osteocytes.

6. 14-3-3 negatively regulates the RGC downstream of the PI3-kinase/Akt signaling pathway

7. 14-3-3 theta is a new and important regulatory protein in the TLR-2 and TLR-4 signaling suppressing the MyD88-dependent pathway