Use your antibodies-online credentials, if available.
Il n’y a pas de produits dans votre liste de comparaison.
Votre panier est vide.
Afficher toutes les espèces
Afficher tous les synonymes
Sélectionnez vos espèces et l'application
anti-Mouse (Murine) STAU1 Anticorps:
anti-Human STAU1 Anticorps:
anti-Rat (Rattus) STAU1 Anticorps:
Vous arrivez à notre recherche pré-filtrée.
The role of Miranda in the localization of Staufen during the division of neuroblasts is described.
Staufen targets coracle mRNA to Drosophila neuromuscular junctions and regulates GluRIIA synaptic accumulation and bouton number.
the expression of Adf (Montrer CFL1 Anticorps)-1 targets Staufen and Fasciclin II (Montrer NCAM2 Anticorps) (FasII), identified through larval brain ChIP-Seq for Adf (Montrer CFL1 Anticorps)-1, is negatively regulated by Adf (Montrer CFL1 Anticorps)-1, and manipulations of these genes predictably modify dendrite growth.
Data propose bicoid mRNA localization was done by Swallow indirectly organizing the cytoskeleton, whereas Staufen plays a direct role in dynein-dependent bicoid mRNA transport.
Miranda has a role in coupling oskar mRNA/Staufen complexes to the bicoid mRNA localization pathway
we suggest a model in which dynein's interaction with Staufen1 regulates mRNA localization along the axon and the synapses, and alterations in this process may correlate with synapse disruption and amyotrophic lateral sclerosis toxicity.
Collectively our results show that Staufen1 is highly expressed during early stages of differentiation/development and that it can impair differentiation by regulating c-myc (Montrer MYC Anticorps) thereby highlighting the multifunctional role of Staufen1 in skeletal muscle cell
For Stau1-mediated mRNA decay, Stau1 binds to the 3' untranslated region of target mRNA and recruits Upf1 (Montrer UPF1 Anticorps) to elicit rapid mRNA degradation.
Dvl2 (Montrer DVL2 Anticorps) has an inhibitory role in myogenesis and Stau1 coordinates myogenesis through the regulation of Dvl2 (Montrer DVL2 Anticorps) mRNA.
Expression of Stau1 in the mouse hippocampus is modulated by a sequence variant (B2 SINE indel) in the 3' UTR (Montrer UTS2R Anticorps) of Comt (catechol-O-methyltransferase (Montrer COMT Anticorps)).
Identification of mRNA/protein (mRNP) complexes and their association with rough endoplasmic reticulum equipeed with a kinesin motor
Results suggest that Stau1 negatively regulates myogenesis in C2C12 myoblasts through a mechanism that is different from Stau1-mediated mRNA decay.
Staufen is present in the preimplantation mouse embryo
Stau1 is crucial for synapse development in vitro but not critical for normal behavioral function
Stau1 is involved in recovery from stress by stabilizing polysomes, thus helping stress granule dissolution.
ADAR1p110 isoform competitively inhibits binding of Staufen1 to the 3'-untranslated-region dsRNAs and antagonizes Staufen1-mediated mRNA decay.
Stau1 is a stress response gene that remains efficiently translated during hypoxia and ER stress despite the substantial global inhibition of cap-dependent protein translation, promoting cell recovery following stress
Our findings suggest that HCV may appropriate Stau1 to its advantage to prevent PKR (Montrer PKLR Anticorps)-mediated inhibition of eIF2alpha (Montrer EIF2A Anticorps), which is required for the synthesis of HCV proteins for translocation of viral RNA genome to the polysomes for efficient translation and replication.
together, these data highlight the broad impact of Stau1 as a splicing regulator and suggest that Stau1 may act as a disease modifier in DM1.
expression of human Staufen1 is essential for proper dendritic arborisation during neuroblastoma (Montrer ARHGEF16 Anticorps) cell differentiation, yet it is not necessary for maintenance of differentiated state, and suggest potential human Stauf1 mRNA targets involved in the process
The changing pattern of STAU distribution during meiotic maturation of human oocytes implicates a novel mechanism for the regulation of protein synthesis based on mRNA localization
in vivo atlas of mRNA secondary structures recognized by Staufen 1
TINCR, together with Staufen1, seems to stabilize a subset of mRNAs required for epidermal differentiation.
Staufen1 is an important factor in HCV replication and it might play a role early in the HCV replication cycle, rather than virion morphogenesis.
STAU1 binding to a 3'-UTR (Montrer UTS2R Anticorps) SBS (Montrer CYLD Anticorps) was previously shown to trigger STAU1-mediated mRNA decay (SMD) by directly recruiting the ATP-dependent RNA helicase (Montrer DDX52 Anticorps) UPF1 (Montrer UPF1 Anticorps)
STAU1 & STAU2 & ELAVL1 (Montrer ELAVL1 Anticorps) mRNAs & proteins were detected throughout cow preimplantation development (Montrer MTA2 Anticorps) from the germinal vesicle (GV) oocyte to the blastocyst stage; ELAVL2 (Montrer ELAVL2 Anticorps) mRNAs were detectable from the GV to the morula stage; ELAVL2 (Montrer ELAVL2 Anticorps) protein was in all stages
present in a ribonucleoprotein complex; associates with both a kinesin motor protein (Montrer KIF16B Anticorps) and vegetally localized RNAs Vg1 and VegT; results suggest a central role for Staufen in RNA localization in Xenopus oocytes
Maternally expressed staufen is dispersed in the mature oocyte and early embryo. In the adult, staufen is expressed in specific brain nuclei, the testis, neurons and Leydig cells
stau1 is required for the survival and migration of primordial germ cells.
Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5'UTR.
staufen, RNA binding protein, homolog 1 (Drosophila)
, double-stranded RNA-binding protein Staufen homolog 1
, double-stranded RNA-binding protein Staufen homolog 1-like
, staufen, RNA binding protein, homolog 1
, Staufen 1
, RNA binding protein homolog
, staufen RNA binding protein homolog 1