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Aurora Kinase A Produits

(Aurora Kinase A (AURKA))
The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].

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Catégories Aurora Kinase A en vedette

Aurora Kinase A Anticorps

High quality antibodies with extensive validation data.

Aurora Kinase A Kits ELISA

Reliable ELISA kits for a wide range of species.

Aurora Kinase A Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Aurora Kinase A recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC, FACS, ICC
Validations
  • (9)
N° du produit ABIN5611121
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Human
Application WB, IF, IHC (p), ICC
Validations
  • (7)
N° du produit ABIN2855868
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (2)
  • (5)
N° du produit ABIN563053
Quantité 100 μg
Fiche technique Fiche technique

Aurora Kinase A recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6965093
Quantité 96 tests
Fiche technique Fiche technique

Aurora Kinase A recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (2)
N° du produit ABIN1346206
Quantité 25 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect cells (Sf21)
Validations
  • (2)
N° du produit ABIN5570517
Quantité 5 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect cells (Sf9)
Validations
  • (2)
N° du produit ABIN5570516
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits Aurora Kinase A

So, Seres, Steyer, Mönnich, Clift, Pejkovska, Möbius, Schuh: "A liquid-like spindle domain promotes acentrosomal spindle assembly in mammalian oocytes." dans: Science (New York, N.Y.), Vol. 364, Issue 6447, (2019) (PubMed).

Vallot, Leontiou, Cladière, El Yakoubi, Bolte, Buffin, Wassmann: "Tension-Induced Error Correction and Not Kinetochore Attachment Status Activates the SAC in an Aurora-B/C-Dependent Manner in Oocytes." dans: Current biology : CB, Vol. 28, Issue 1, pp. 130-139.e3, (2018) (PubMed).

Drpic, Almeida, Aguiar, Renda, Damas, Lewin, Larkin, Khodjakov, Maiato: "Chromosome Segregation Is Biased by Kinetochore Size." dans: Current biology : CB, Vol. 28, Issue 9, pp. 1344-1356.e5, (2018) (PubMed).

Kovarikova, Burkus, Rehak, Brzakova, Solc, Baran: "Aurora kinase A is essential for correct chromosome segregation in mouse zygote." dans: Zygote (Cambridge, England), Vol. 24, Issue 3, pp. 326-37, (2016) (PubMed).

Flores, Castilla, Gasca, Medina, Pérez-Valderrama, Romero, Japón, Sáez: "Loss of PKCδ Induces Prostate Cancer Resistance to Paclitaxel through Activation of Wnt/β-Catenin Pathway and Mcl-1 Accumulation." dans: Molecular cancer therapeutics, Vol. 15, Issue 7, pp. 1713-25, (2016) (PubMed).

Gasca, Flores, Giráldez, Ruiz-Borrego, Tortolero, Romero, Japón, Sáez: "Loss of FBXW7 and accumulation of MCL1 and PLK1 promote paclitaxel resistance in breast cancer." dans: Oncotarget, (2016) (PubMed).

Casorzo, DellAglio, Sarotto, Risio: "Aurora kinase A gene copy number is associated with the malignant transformation of colorectal adenomas but not with the serrated neoplasia progression." dans: Human pathology, Vol. 46, Issue 3, pp. 411-8, (2015) (PubMed).

Mahdipour, Leitoguinho, Zacarias Silva, van Tol, Stout, Rodrigues, Roelen: "TACC3 Is Important for Correct Progression of Meiosis in Bovine Oocytes." dans: PLoS ONE, Vol. 10, Issue 7, pp. e0132591, (2015) (PubMed).

Premkumar, Jane, Pollack et al.: "Cucurbitacin-I inhibits Aurora kinase A, Aurora kinase B and survivin, induces defects in cell cycle progression and promotes ABT-737-induced cell death in a caspase-independent manner in malignant ..." dans: Cancer biology & therapy, Vol. 16, Issue 2, pp. 233-43, (2015) (PubMed).

Hsu, Chen, Yeh, Yen, Wu, Hsu, Hsu, Chou: "TPX2 expression is associated with cell proliferation and patient outcome in esophageal squamous cell carcinoma." dans: Journal of gastroenterology, Vol. 49, Issue 8, pp. 1231-40, (2014) (PubMed).

Synonymes et noms alternatifs relatifs à Aurora Kinase A

aurora kinase A (AURKA), aurora kinase A (Aurka), aurora A (aurA), aurora kinase A L homeolog (aurka.L), aurora kinase A (aurka), hypothetical protein (Aurora-A), aurora kinase A S homeolog (aurka.S), 87A7-9/2, AIK, aik, AIRK1, ARK-1, ARK1, Ark1, ark1, AU019385, Aur-A, aur-A, aur-a, AURA, AurA, aurA, aura, AURKA, aurka, aurka-a, Aurora-A, AURORA2, aurora2, AW539821, Ayk1, BTAK, btak, CG3068, ck10, ck[10], Dmel\\CG3068, Eg2, IAK, IAK1, l(3)87Ac, l(3)ck10, pEg2, PPP1R47, STK6, Stk6, stk6, STK7, stk7, STK15, stk15, wu:fb37c10, wu:fc02c02, zgc:100912

Protein level used designations for Aurora Kinase A

  • ARK-1
  • Aurora-A kinase
  • IPL1-related kinase
  • aurora 2
  • aurora-related kinase 1
  • aurora/IPL1-like kinase
  • aurora/IPL1-related kinase 1
  • breast tumor-amplified kinase
  • breast-tumor-amplified kinase
  • hARK1
  • protein phosphatase 1, regulatory subunit 47
  • serine/threonine kinase 6
  • serine/threonine protein kinase 15
  • serine/threonine-protein kinase 15
  • serine/threonine-protein kinase 6
  • serine/threonine-protein kinase aurora-A
  • aurora A
  • aurora family kinase 1
  • ipl1- and aurora-related kinase 1
  • serine/threonine-protein kinase Ayk1
  • A-type aurora kinase
  • AuroraA
  • CG3068-PA
  • aur-PA
  • aurora A kinase
  • aurora kinase
  • aurora-A
  • early-A
  • fruhe2
  • ratAurA
  • serine/threonine protein kinase 6
  • Aurora A
  • aurora kinase A-A
  • p46Eg265
  • pEg2
  • serine/threonine-protein kinase 6-A
  • serine/threonine-protein kinase Eg2
  • serine/threonine-protein kinase Eg2-A
  • Aurora-A
  • Serine/threonine-protein kinase 6
  • hypothetical protein
  • aurora kinase A
  • fb37c10
  • fc02c02
  • aurora A kinase protein
  • serine/threonine-protein kinase 6-like
  • aurora kinase A-B
  • serine/threonine-protein kinase 6-B
  • serine/threonine-protein kinase Eg2-B
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