Caspase 12 (Gene/pseudogene) Produits
(Caspase 12 (Gene/pseudogene) (CASP12))
Catégories
Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Feb 2011].
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Catégories Caspase 12 (Gene/pseudogene) en vedette
Caspase 12 (Gene/pseudogene) Anticorps
High quality antibodies with extensive validation data.
Caspase 12 (Gene/pseudogene) Kits ELISA
Reliable ELISA kits for a wide range of species.
Caspase 12 (Gene/pseudogene) Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Caspase 12 (Gene/pseudogene) recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (10)
N° du produit
ABIN7442993
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (7)
N° du produit
ABIN7440263
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Mouse, Rat
Application
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Validations
- (8)
- (5)
N° du produit
ABIN737736
Quantité
100 μL
Fiche technique
Fiche technique
Caspase 12 (Gene/pseudogene) recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6965454
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6965453
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6965452
Quantité
96 tests
Fiche technique
Fiche technique
Caspase 12 (Gene/pseudogene) recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3090819
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7415872
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7422757
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Caspase 12 (Gene/pseudogene)
: "Modulation of mitochondrial phenotypes by endurance exercise contributes to neuroprotection against a MPTP-induced animal model of PD." dans: Life sciences, Vol. 209, pp. 455-465, (2018) (PubMed).: "Ibutilide treatment protects against ER stress induced apoptosis by regulating calumenin expression in tunicamycin treated cardiomyocytes." dans: PLoS ONE, Vol. 12, Issue 4, pp. e0173469, (2017) (PubMed).
: "Gypenoside Protects against Myocardial Ischemia-Reperfusion Injury by Inhibiting Cardiomyocytes Apoptosis via Inhibition of CHOP Pathway and Activation of PI3K/Akt Pathway In Vivo and In Vitro." dans: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 39, Issue 1, pp. 123-36, (2016) (PubMed).
: "Ibutilide protects against cardiomyocytes injury via inhibiting endoplasmic reticulum and mitochondrial stress pathways." dans: Heart and vessels, (2016) (PubMed).
: "Epigallocatechin-3-gallate pretreatment attenuates doxorubicin-induced cardiotoxicity in rats: A mechanistic study." dans: Biochemical pharmacology, Vol. 95, Issue 3, pp. 145-55, (2015) (PubMed).
: "Sulfiredoxin-1 exerts anti-apoptotic and neuroprotective effects against oxidative stress-induced injury in rat cortical astrocytes following exposure to oxygen-glucose deprivation and hydrogen ..." dans: International journal of molecular medicine, Vol. 36, Issue 1, pp. 43-52, (2015) (PubMed).
: "Increased expression of 78 kD glucose-regulated protein promotes cardiomyocyte apoptosis in a rat model of liver cirrhosis." dans: International journal of clinical and experimental pathology, Vol. 8, Issue 8, pp. 9256-63, (2015) (PubMed).
: "Glucose-regulated protein 78 may play a crucial role in promoting the pulmonary microvascular remodeling in a rat model of hepatopulmonary syndrome." dans: Gene, Vol. 545, Issue 1, pp. 156-62, (2014) (PubMed).
: "Zinc chloride inhibits human lens epithelial cell migration and proliferation involved in TGF-β1 and TNF-α signaling pathways in HLE B-3 cells." dans: Biological trace element research, Vol. 159, Issue 1-3, pp. 425-33, (2014) (PubMed).
: "Evodiamine induces G2/M arrest and apoptosis via mitochondrial and endoplasmic reticulum pathways in H446 and H1688 human small-cell lung cancer cells." dans: PLoS ONE, Vol. 9, Issue 12, pp. e115204, (2014) (PubMed).
Synonymes et noms alternatifs relatifs à Caspase 12 (Gene/pseudogene)
caspase 12 (Casp12), caspase 12 (CASP12), caspase 12 (gene/pseudogene) (CASP12), CASP-12, CASP12P1, Caspase-12Protein level used designations for Caspase 12 (Gene/pseudogene)
- CASP-12
- caspase-12
- caspase 12 pseudogene 1
- inactive caspase-12
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