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anti-Human TJP1 Anticorps:
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Human Polyclonal TJP1 Primary Antibody pour IF (cc), IF (p) - ABIN675024
Gu, Xue, Wei, Zhang, Li: Calcium-activated potassium channel activator down-regulated the expression of tight junction protein in brain tumor model in rats. dans Neuroscience letters 2011
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Human Monoclonal TJP1 Primary Antibody pour IF, WB - ABIN968282
Ebnet, Schulz, Meyer Zu Brickwedde, Pendl, Vestweber: Junctional adhesion molecule interacts with the PDZ domain-containing proteins AF-6 and ZO-1. dans The Journal of biological chemistry 2000
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Human Monoclonal TJP1 Primary Antibody pour IF, WB - ABIN968283
Hirase, Kawashima, Wong, Ueyama, Rikitake, Tsukita, Yokoyama, Staddon: Regulation of tight junction permeability and occludin phosphorylation by Rhoa-p160ROCK-dependent and -independent mechanisms. dans The Journal of biological chemistry 2001
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Human Polyclonal TJP1 Primary Antibody pour ICC, IF - ABIN4359733
Gangl, Reininger, Bernhard, Campana, Pree, Reisinger, Kneidinger, Kundi, Dolznig, Thurnher, Valent, Chen, Vrtala, Spitzauer, Valenta, Niederberger: Cigarette smoke facilitates allergen penetration across respiratory epithelium. dans Allergy 2009
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Human Polyclonal TJP1 Primary Antibody pour IF - ABIN2192206
Balda, Anderson: Two classes of tight junctions are revealed by ZO-1 isoforms. dans The American journal of physiology 1993
Human Polyclonal TJP1 Primary Antibody pour ICC, IF - ABIN4359735
McIntyre, Alev, Mechael, Salci, Lee, Fiebig-Comyn, Guezguez, Wu, Sheng, Bhatia: Expansive generation of functional airway epithelium from human embryonic stem cells. dans Stem cells translational medicine 2014
Human Polyclonal TJP1 Primary Antibody pour ELISA, WB - ABIN4359730
Zhong, Deane, Ali, Parisi, Shapovalov, OBanion, Stojanovic, Sagare, Boillee, Cleveland, Zlokovic: ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration. dans Nature neuroscience 2008
the Ras signaling pathway is involved in HIV-1 Tat (Montrer TAT Anticorps)-induced changes in ZO-1 and NEP (Montrer MME Anticorps).
decreased interaction between ZO-1 and occludin (Montrer OCLN Anticorps) might contribute to the epiphora occurred in the transplanted submandibular glands
integration of claudin-2 (Montrer CLDN2 Anticorps), occludin (Montrer OCLN Anticorps) and ZO-1 is necessary for maintaining the function of the proximal tubular epithelium.
Endothelial cellsTLR4 strongly regulates retinal vessel permeability by reducing expression of occludin (Montrer OCLN Anticorps) and zonula occludens 1.
The role of estrogens in the regulation of ZO-1 and estrogen receptors 1 and 2 was evaluated in human primary gut (Montrer GUSB Anticorps) tissues by immunohistochemistry, immunofluorescence and qPCR.
Aberrant expression of the tight junction molecules claudin-1 (Montrer CLDN7 Anticorps) and zonula occludens-1 mediates cell growth and invasion in oral squamous cell carcinoma cells.
ZO-1-occludin (Montrer OCLN Anticorps) interactions regulate multiple phases of epithelial polarization by providing cell-intrinsic signals that are required for single lumen formation.
It is postulated that ZO-1, when not phosphorylated by PKC (Montrer PRRT2 Anticorps), keeps Octn2 (Montrer SLC22A5 Anticorps) in an active state, while elimination of this binding in DeltaPDZ mutant or after ZO-1 phosphorylation leads to diminution of Octn2 (Montrer SLC22A5 Anticorps) activity.
Results uncovered ZO-1 as part of a signaling node activated by VEGF (Montrer VEGFA Anticorps), but not Ang-1 (Montrer ANGPT1 Anticorps), that specifically modulates endothelial cells proliferation during angiogenesis.
Data suggest that long noncoding RNA PlncRNA1 and microRNA miR (Montrer MLXIP Anticorps)-34c bound together to regulate the expressions of MAZ (Montrer MAZ Anticorps), ZO-1 and occludin (Montrer OCLN Anticorps).
STAT3 activation downregulates the ZO-1 and occludin levels and increases the endothelial permeability through the induction of VEGF production in retinal endothelial cells.
Cx43 (Montrer GJA1 Anticorps) tethers the F-actin cytoskeleton through a ZO-1 linker and supports cell spreading and exploration during locomotion in cerebral endothelial cells.
Expression of Podocalyxin (Montrer PODXL Anticorps), which positively regulates the formation of microvilli and the apical membrane, is repressed in embryoid bodies lacking both ZO-1 and ZO-2 (Montrer TJP2 Anticorps) and this correlates with an aberrant submembranous localization of Ezrin (Montrer EZR Anticorps).
Zonula occludens-1, occludin (Montrer OCLN Anticorps) and E-cadherin (Montrer CDH1 Anticorps) expression and organization in salivary glands
Tjp1 expression was decreased in glomerular diseases in human and animal models, our results indicate that the suppression of Tjp1 could directly aggravate glomerular disorders, highlights Tjp1 as a potential therapeutic target.
Arecoline increases the production of TNF-alpha (Montrer TNF Anticorps) and induces protein redistribution of ZO-1.
Vcl (Montrer VCL Anticorps) plays a crucial role in stabilizing gap junctions and myocyte integrity through direct interactions with ZO-1 and stabilization of CX43 (Montrer GJA1 Anticorps).
Activation of RhoA (Montrer RHOA Anticorps)/ROCK1 (Montrer ROCK1 Anticorps) by high glucose in diabetic nephropathy disrupts the expression and translocation of occludin (Montrer OCLN Anticorps)/ZO-1, which can be corrected by simvastatin.
Vascular endothelial tight junctions and barrier function are disrupted by 15(S)-hydroxyeicosatetraenoic acid partly via protein kinase C epsilon (Montrer PRKCE Anticorps)-mediated zona occludens-1 phosphorylation at threonine 770/772.
cyclic strain modulates both the expression and phosphorylation state of occludin (Montrer OCLN Anticorps) and ZO-1 in vascular endothelial cells, with putative consequences for endothelial tight junction assembly and barrier integrity
ZO-1 and occludin (Montrer OCLN Anticorps) are expressed in oocytes and preimplantation embryos, and that ZO-1alpha+ is transcribed by zygotic gene activation and translated from early blastocysts with prominent increase of occludin (Montrer OCLN Anticorps) at the blastocyst stage.
This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for this gene.
tight junction protein ZO-1
, zona occludens 1
, zona occludens protein 1
, zonula occludens 1 protein
, zonula occludens protein 1
, tight junction protein 1 (zona occludens 1)
, zonula occludens 1