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Human Polyclonal Peroxiredoxin 5 Primary Antibody pour ELISA, WB - ABIN565177
Wang, Du, Liu, Gao, Meng, Guan, Zhang: TNF-related apoptosis-inducing ligand suppresses PRDX4 expression. dans FEBS letters 2009
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Dog (Canine) Polyclonal Peroxiredoxin 5 Primary Antibody pour WB - ABIN2785911
Trujillo, Clippe, Manta, Ferrer-Sueta, Smeets, Declercq, Knoops, Radi: Pre-steady state kinetic characterization of human peroxiredoxin 5: taking advantage of Trp84 fluorescence increase upon oxidation. dans Archives of biochemistry and biophysics 2007
results suggest JNK (Montrer MAPK8 Anticorps)/FOXO (Montrer FOXO Anticorps) mediated dPrxV (Peroxiredoxin 5) expression plays a critical role in Drosophila melanogaster gut (Montrer GUSB Anticorps) during bacterial infection in protecting the host gut (Montrer GUSB Anticorps) epithelial cells from oxidative damage
flies underexpressing peroxiredoxin 3 (Montrer PRDX3 Anticorps) and peroxiredoxin 5 showed an 80% reduction in lifespan and a massive induction of apoptosis in the muscle and digestive system tissues
Overexpressiion of Prx5 were more susceptible to bacterial infection in Drosophila melanogaster .
the antioxidant and anti-apoptotic activities of dPrx5 play a critical role in development and aging of the fly
Results found that Prx5 was increased in the cellular model of Alzheimer's disease (AD) and, identify a role for Prx5 as an upregulator of Cdk5 activation via reactive oxygen species-mediated Ca2+-mediated calpain activation.
The PRX5 can be used as a predictive biomarker and serves as a putative therapeutic target for the development of clinical treatments for human CRC (Montrer CALR Anticorps).
peroxisomal PRDX5 protects oligodendrocytes against peroxisomal and mitochondrial oxidative stress.
show here how the ligand-observed saturation transfer difference (STD (Montrer SULT2A1 Anticorps)) experiment and the PRDX5 protein-observed 15N-HSQC experiment, two popular NMR screening experiments, can be used to compare the binding modes of analogous fragments
PRX5 is either consumed or its production is impaired in severe stroke
This study demonistrated that overexpression of mitochondrial PRDX5 protects SH-SY5Y cells against the ROS (Montrer ROS1 Anticorps)/RNS (Montrer FAM20C Anticorps)-dependent neuronal death induced by MPP (Montrer MPZ Anticorps)+.
The promoter region critical for Prx5 gene regulation to which the novel negative transcription regulator, GATA1 (Montrer GATA1 Anticorps) binds in human breast cancer cell lines.
basal expression of the human PRDX5 gene is regulated by GABP
analysis of fragment molecules that bind the human peroxiredoxin 5 active site
Glutaredoxin (Montrer GRX1 Anticorps)-dependent peroxiredoxin from poplar: protein-protein interaction and catalytic mechanism
PRX1 (Montrer PRDX1 Anticorps) and PRX5 were upregulated in osteoblasts in the proximal tibial metaphysis of ovariectomized mice. Interestingly, PRX1 (Montrer PRDX1 Anticorps) and PRX5 showed different distribution patterns, with PRX1 (Montrer PRDX1 Anticorps) mainly accumulated in cell nuclei and PRX5 in the cytoplasm.
The ventral signal observed from E12.5 on colocalized with motor neuron markers Isl1 (Montrer ISL1 Anticorps)/2 and FoxP1 (Montrer FOXP1 Anticorps) and The strong ventral signal colocalizing wtth Isl1 (Montrer ISL1 Anticorps)/2 was observed in all rostrocaudal segments of the spinal cord.
results suggest that PrdxV is a key mediator contributing to the regulation of LPS/TLR4 (Montrer TLR4 Anticorps)-induced immune responses
IMS-PRDX5 (Montrer PRDX6 Anticorps) expression also attenuates the increase in cytosolic [Ca(2 (Montrer CA2 Anticorps)+)] in PASMCs during hypoxia.
The SirT1 (Montrer SIRT1 Anticorps) regulates the expression of several antioxidant genes in bovine aortic endothelial cells, including Mn superoxide dismutase (Montrer SOD2 Anticorps), catalase (Montrer CAT Anticorps), peroxiredoxins 3 and 5, thioredoxin 2 (Montrer TXN2 Anticorps), thioredoxin reductase 2 (Montrer TXNRD2 Anticorps), and uncoupling protein 2 (Montrer UCP2 Anticorps).
Prx V plays a key role in the microglial activation process through modulation of the balance between ROS (Montrer ROS1 Anticorps)/NO generation and the corresponding JNK (Montrer MAPK8 Anticorps) cascade activation.
PRDX5 (Montrer PRDX6 Anticorps) has a role in neuroprotection
Prx5 levels also appear to be highly dependent on c-Myc (Montrer MYC Anticorps), and chromatin immunoprecipitation experiments showed differential occupancy of c-Myc (Montrer MYC Anticorps) and Prx1 (Montrer PRDX1 Anticorps) complexes at E-box elements in the prx5 gene proximal promoter
These results suggest that the antioxidant and antiapoptotic activities of PRDX5 play important roles in the in vitro development of bovine SCNT embryos.
Bovine cauda sperm PRDX5 acts as an antioxidant enzyme in the epididymal environment.
This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. This protein interacts with peroxisome receptor 1. The crystal structure of this protein in its reduced form has been resolved to 1.5 angstrom resolution. This gene uses alternate in-frame translation initiation sites to generate mitochondrial or peroxisomal/cytoplasmic forms. Three transcript variants encoding distinct isoforms have been identified for this gene.
, peroxiredoxin 5
, Alu co-repressor 1
, TPx type VI
, antioxidant enzyme B166
, liver tissue 2D-page spot 71B
, peroxiredoxin V
, peroxisomal antioxidant enzyme
, thioredoxin peroxidase PMP20
, thioredoxin reductase
, liver tissue 2D-page spot 2D-0014IV
, peroxiredoxin 6
, peroxisomal membrane protein 20