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anti-Human ABCA1 Anticorps:
anti-Rat (Rattus) ABCA1 Anticorps:
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Chicken Polyclonal ABCA1 Primary Antibody pour ChIP, ELISA - ABIN152883
Krimbou, Denis, Haidar, Carrier, Marcil, Genest: Molecular interactions between apoE and ABCA1: impact on apoE lipidation. dans Journal of lipid research 2004
Show all 259 Pubmed References
Chicken Polyclonal ABCA1 Primary Antibody pour ELISA, ICC - ABIN268847
Burgess, Kiss, Zheng, Zachariah, Marcel: Trypsin-sensitive and lipid-containing sites of the macrophage extracellular matrix bind apolipoprotein A-I and participate in ABCA1-dependent cholesterol efflux. dans The Journal of biological chemistry 2002
Show all 13 Pubmed References
Chicken Polyclonal ABCA1 Primary Antibody pour ELISA, IHC (fro) - ABIN268848
Murthy, Born, Mathur, Field: LXR/RXR activation enhances basolateral efflux of cholesterol in CaCo-2 cells. dans Journal of lipid research 2002
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Mouse (Murine) Monoclonal ABCA1 Primary Antibody pour IHC (p), WB - ABIN268899
Zhou, Choi, Li, Xu, Herz: LRP1 controls cPLA2 phosphorylation, ABCA1 expression and cellular cholesterol export. dans PLoS ONE 2009
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Human Polyclonal ABCA1 Primary Antibody pour WB - ABIN3043773
Shang, Yu, Wang, Chen, Fang, Yang, Zhou, Nie, Zhou, Zhou: Fibroblast growth factor 21 enhances cholesterol efflux in THP-1 macrophage-derived foam cells. dans Molecular medicine reports 2014
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Human Polyclonal ABCA1 Primary Antibody pour WB - ABIN3044206
Chen: Effects of Chinese Herbal Compound "Xuemai Ning"on Rabbit Atherosclerosis Model and Expression of ABCA1. dans International journal of biomedical science : IJBS 2013
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Human Monoclonal ABCA1 Primary Antibody pour CyTOF, FACS - ABIN4277133
Wang, Zhang, Chou, Liang, Gu, Ma: Cyclosporine stimulates the renal epithelial sodium channel by elevating cholesterol. dans American journal of physiology. Renal physiology 2009
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Human Polyclonal ABCA1 Primary Antibody pour IF (p), IHC (p) - ABIN732188
Jia, Song, Yang, Ma, Li, Lu, Cao, Zhang, Zhu, Wang, Leng, Cao, Du, Xu: Effects of Tanshinone IIA on the modulation of miR‑33a and the SREBP‑2/Pcsk9 signaling pathway in hyperlipidemic rats. dans Molecular medicine reports 2016
Cow (Bovine) Polyclonal ABCA1 Primary Antibody pour WB - ABIN2781512
Fu, Mukhamedova, Ip, DSouza, Henley, DiTommaso, Kesani, Ditiatkovski, Jones, Lane, Jennings, Smyth, Kile, Sviridov: ABCA12 regulates ABCA1-dependent cholesterol efflux from macrophages and the development of atherosclerosis. dans Cell metabolism 2013
Mouse (Murine) Monoclonal ABCA1 Primary Antibody pour FACS, IF - ABIN2477218
Zarubica, Trompier, Chimini: ABCA1, from pathology to membrane function. dans Pflügers Archiv : European journal of physiology 2007
Confirmed by mRNA and protein expression, the amino acid transporters SLC7A7 (Montrer Slc7a7 Anticorps) and SLC38A5 (Montrer Slc38a5 Anticorps) showed marked differences between controls and intrauterine growth restriction/pre-eclampsia and were regulated by both diseases. In contrast, ABCA1 may play an exclusive role in the development of pre-eclempsia.
Single Nucleotide Polymorphism in ABCA1 gene is associated with dyslipidemia.
Increased expression of hepatic ABCA1 transporter is associated with hypercholesterolemia in a cholestatic rat model and primary biliary cholangitis patients.
Review/Meta-analysis: significant association of ABCA1 rs2230806 GG with increased risk of ischemic stroke.
Results showed that ABCA1 participates in the alpha-synuclein transport of cholesterol through the plasma membrane of neuronal cells.
HECTD1 (Montrer HECTD1 Anticorps) may be involved in the regulation of ABCA1-mediated cholesterol export from unloaded macrophages to apoA-I (Montrer APOA1 Anticorps).
ABCA1 R219K RR+RK genotype frequency in Alzheimer and Parkinson Disease patients was lower than that in normal controls (NC), while ABCA1 R219K KK genotype frequency was significantly higher. ABCA1 R219K R allele was the risk factor inducing abnormal serum levels of ApoA2 (Montrer APOA2 Anticorps), LDL, and TG in AD patients, and abnormal levels of serum ABCA1, HDL (Montrer HSD11B1 Anticorps), IL-1beta (Montrer IL1B Anticorps), IL-6 (Montrer IL6 Anticorps), and TNF-alpha (Montrer TNF Anticorps) in PD patients.
This study provides evidence that, in HepG2 cells, GLP-1 (Montrer GCG Anticorps) may affect cholesterol homeostasis by regulating the expression of miR (Montrer MLXIP Anticorps)-758 and ABCA1.
Hsp27 (Montrer HSPB1 Anticorps) may up-regulate the expression of ABCA1 and promotes cholesterol efflux through activation of the PI3K (Montrer PIK3CA Anticorps)/PKCzeta (Montrer PRKCZ Anticorps)/Sp1 (Montrer PSG1 Anticorps) signal pathway in THP-1 (Montrer GLI2 Anticorps) macrophage-derived foam cells
the present study revealed that overexpression of GLP1R (Montrer GLP1R Anticorps) significantly reduces proliferation, migration and cytokine release in ASM (Montrer SMPD1 Anticorps) cells from COPD (Montrer ARCN1 Anticorps) patients; this involved a significant increase in ABCA1 expression levels. This provided evidence to suggest that GLP1R (Montrer GLP1R Anticorps) may be a potential therapeutic target for the treatment of COPD (Montrer ARCN1 Anticorps).
our results highlight the importance of the LXR (Montrer NR1H3 Anticorps)/ABCA1 system in brain pericytes and suggest a new role for these cells in brain cholesterol homeostasis.
The expression and distribution of the bovine ABCA1 transporter using quantitative PCR and the sequencing of the entire ABCA1 coding region, including the proximal promoter region, are reported.
Aortic endothelial cells transcytose high-density lipoproteins by mechanisms that involve either SR-BI (Montrer SCARB1 Anticorps) or ABCG1 (Montrer ABCG1 Anticorps) but not ABCA1.
ABCA1 promoter variants affect transcription activity and plasma HDL (Montrer HSD11B1 Anticorps) level in pigs
ABCA1 was up-regulated in monocytes of hypercholesterolemic pigs via oxidized-LDL and prior to development coronary atherosclerosis.
Both region-specific and ubiquitous (ABCA1) phenotype changes were identified as early prelesional responses of the endothelium to hypercholesterolemia
CSL112 elevation of ABCA1-dependent efflux may target atherosclerotic plaque for cholesterol removal.
these results suggest that apigenin may attenuate atherogenesis through up-regulating ABCA1-mediated cholesterol efflux and inhibiting inflammation.
TMP upregulated the protein stability of ABCA1 without affecting ABCG1 (Montrer ABCG1 Anticorps). Accordingly, TMP regulated the expression of SR-A (Montrer MSR1 Anticorps), CD36 (Montrer CD36 Anticorps), ABCA1 and ABCG1 (Montrer ABCG1 Anticorps) in aortas of ApoE (Montrer APOE Anticorps)-/- mice, which resembled the findings observed in macrophages.
HDL3, by interacting with ABCA1, modulates the miR143/145-myocardin (Montrer MYOCD Anticorps) axis and prevents the cholesterol-induced gene expression modification in smooth muscle cells regardless of its cholesterol unloading capacity.
(1) ABCA1 maintains optimal hepatocyte PM FC, through intracellular FC trafficking, for efficient insulin (Montrer INS Anticorps) signaling; and (2) hepatocyte ABCA1 deletion produces a form of selective insulin (Montrer INS Anticorps) resistance so that lipogenesis is suppressed but glucose metabolism remains normal
demonstrates behavior deficits caused by Abca1 deletion in APP (Montrer APP Anticorps)/PS1DeltaE9 mouse model at an early stage of amyloid pathology. The basal deficits of Abca1ko, manifested by diminished cognitive performance, prevent them from coping with additional stressors, which is in part due to the impairment of neurite morphology in the hippocampus.
Rutaecarpine was identified to be a candidate that protected ApoE (Montrer APOE Anticorps)(-/-) mice from developing atherosclerosis through preferentially promoting activities of ABCA1 and SR-BI (Montrer SCARB1 Anticorps) within RCT (Montrer FOXE3 Anticorps).
Abca1 has a protective role in atherosclerosis, it exerts detrimental effects on cardiac function after myocardial infarction
Caveolin-1 (Montrer CAV1 Anticorps) enhances internalization and degradation of ABCA1 by its association with ABCA1
ABCA1-derived nascent high-density lipoprotein-apolipoprotein AI (Montrer APOA1 Anticorps) and lipids metabolically segregate.
an important role for hepatic ABCA1 in regulating secretory trafficking and modulating VLDL expansion during the TG accretion phase of hepatic lipoprotein particle assembly
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency.
ATP-binding cassette sub-family A member 1
, ATP-binding cassette transporter A1
, cholesterol efflux regulatory protein
, ATP-binding cassette, sub-family A (ABC1), member 1
, ATP-binding cassette, sub-family A member 1
, ATP-binding cassette transporter 1
, Cholesterol efflux regulatory protein
, ATP-binding cassette transporter
, ATP-binding cassette, sub-family A member 1-like
, ATP-binding cassette sub-family A member 1-like
, ATP-binding cassette 1