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anti-Human Cathelicidin Anticorps:
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Human Polyclonal Cathelicidin Primary Antibody pour IHC, ELISA - ABIN1002041
Zaiou, Gallo: Cathelicidins, essential gene-encoded mammalian antibiotics. dans Journal of molecular medicine (Berlin, Germany) 2002
Show all 4 Pubmed References
these data show that LL-37 affects surface and intracellular Toll (Montrer TLR4 Anticorps)-Like Receptor expression in tissue mast cells
This review describes novel advances involving the roles and mechanisms of human cathelicidin LL-37 in cancer.
The findings support a role for STAT3 (Montrer STAT3 Anticorps) and HIF-1A (Montrer HIF1A Anticorps) in the regulation of LL-37 expression.
In silico docking study have confirmed the high binding affinities of multiple 9-mer peptides derived from LL-37 to the HLA-C*06:02 molecule proposed a mechanism of the interaction between this LL-37-HLA-C*06:02 complex and T cells via TCRs.
IL-33 (Montrer IL33 Anticorps) down-regulates the induction of hCAP-18/LL-37 production in human gingival epithelial cells.
in teens with positive recto-vaginal group B streptococcus colonization, placental mRNA expression of cathelicidin is lower compared to those who tested negative for this infection
these results suggested that human CAMP/LL-37 might act as a tumor-suppressor in OSCC and DNA methylation (Montrer HELLS Anticorps) might play roles during carcinogenesis via directly downregulating human CAMP promoter activity.
omoted epithelial and smooth-muscle-like differentiation of Adipose-derived stem cells through activating the Wnt (Montrer WNT2 Anticorps)/beta-catenin (Montrer CTNNB1 Anticorps) and NF-kappaB (Montrer NFKB1 Anticorps) pathways, respectively
Patients with type 1 diabetes and presence of microangiopathy characterize higher level of serum cathelicidin.
The expression of LL-37 was up-regulated in the inflamed mucosa of IBD patients. LL-37 was induced by TLR-3 (Montrer TLR3 Anticorps) stimulation and exhibited an anti-microbial effect via interaction with lipopolysaccharide (LPS (Montrer IRF6 Anticorps)).
Injection of CAP18 into juvenile rainbow trout before exposure to Yersinia ruckeri was associated with lowered mortality compared to non-medicated fish although it was less effective than the conventional antibiotic oxolinic acid.
Pattern recognition receptors such as TLR5 (Montrer TLR5 Anticorps) may be involved in the stimulation of cathelicidin expression, and the signalling cascade can include PI3-kinase (Montrer PIK3CA Anticorps) and cellular trafficking compartments.
p15 (Montrer CDKN2B Anticorps) proteins are stored in the specific (secondary) granules of rabbit neutrophils and are secreted extracellularly after inflammatory stimulation.
The p15 (Montrer CDKN2B Anticorps) proteins exhibit antimicrobial synergy with another rabbit cathelicidin (CAP-18) and with the rabbit Bactericidal/permeability-increasing protein (BPI (Montrer BPI Anticorps)).
Immunoblotting, qPCR, ChIP and siRNA-mediated gene knockdown studies revealed that the activation of phosphatidylinositol 3-kinase/protein kinase C zeta (Montrer PRKCZ Anticorps) pathways in poly(I:C)-stimulated cells underlies Sp1 (Montrer SP1 Anticorps) phosphorylation and recruitment to the mCRAMP promoter, leading to enhanced transcription
The effect on insulin (Montrer INS Anticorps) resistance found in Cramp-/- mice is solely due to leukocyte infiltration and not due to inflammatory phenotype of macrophages. Therefore we conclude that cathelicidin causes insulin (Montrer INS Anticorps) resistance by the recruitment of myeloid cells into the adipose tissue.
Cathelicidin is required for innate resistance to M. tuberculosis in a relevant animal model and is a key mediator in regulation of the levels of pro-inflammatory cytokines by calcium and cyclic nucleotides.
overexpressed CRAMP in prostate tumor initially chemoattracts early myeloid progenitors to tumor microenvironment and mediates differentiation and polarization of early myeloid progenitors into protumorigenic M2 macrophages during PCa (Montrer ENPP1 Anticorps) progression
The aim of this project was to examine the functional impact of the human cathelicidin LL-37 and the mouse cathelicidin-related AMP (Montrer TMPRSS5 Anticorps) (CRAMP) on the pathogenesis of lupus and arthritis.
Cathelicidin, expressed by immune cells in the tumor microenvironment, promotes colon cancer growth through activation of the PTEN/PI3K/Akt (Montrer AKT1 Anticorps) and Wnt (Montrer WNT2 Anticorps)/beta-catenin (Montrer CTNNB1 Anticorps) signaling pathways.
pancreatic beta-cells' production is controlled by short-chain fatty acids produced by the gut (Montrer GUSB Anticorps) microbiota, and is defective in non-obese diabetic (NOD) mice
Data indicate the role of cathelicidin-related antimicrobial peptide (CRAMP) as part of the innate immune defense against pathogens in bacterial CNS infections.
Hypoxia-inducible factor-1alpha (HIF-1alpha (Montrer HIF1A Anticorps)), a transcription factor important for activating innate immune effectors, and the antimicrobial peptide LL-37 (CRAMP in mice) are key determinants of C. albicans colonization resistance.
Specific structural motifs in syndecan-1 (Montrer SDC1 Anticorps) HS promote Staphylococcus aureus corneal infection by inhibiting neutrophil CRAMP.
Characterization of single nucleotide polymorphisms (SNPs) and insertion-deletion (indel) polymorphisms within the bovine CATHL (Montrer CTSL1 Anticorps) gene family.
This gene encodes a member of an antimicrobial peptide family, characterized by a highly conserved N-terminal signal peptide containing a cathelin domain and a structurally variable cationic antimicrobial peptide, which is produced by extracellular proteolysis from the C-terminus. The encoded protein has several functions in addition to antimicrobial activity, including cell chemotaxis, immune mediator induction and inflammatory response regulation.
18 kDa cationic antimicrobial protein
, cathelicidin antimicrobial peptide
, cathelicidin-derived antimicrobial peptide 2
, 18 kDa cationic protein
, 18 kDa lipopolysaccharide-binding protein
, antimicrobial protein CAP18
, cathelin-like protein
, cathelin-related antimicrobial peptide
, cathelicidin 2
, myeloid antimicrobial peptide 27
, antimicrobial peptide
, antibacterial peptide BMAP-34
, cathelicidin 7
, neutrophil cationic antibacterial polypeptide of 11 kDa