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anti-Human CXCL3 Anticorps:
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Human Polyclonal CXCL3 Primary Antibody pour WB - ABIN2792197
Tekamp-Olson, Gallegos, Bauer, McClain, Sherry, Fabre, van Deventer, Cerami: Cloning and characterization of cDNAs for murine macrophage inflammatory protein 2 and its human homologues. dans The Journal of experimental medicine 1990
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Human Polyclonal CXCL3 Primary Antibody pour Func, IHC (p) - ABIN2473898
Haskill, Peace, Morris, Sporn, Anisowicz, Lee, Smith, Martin, Ralph, Sager: Identification of three related human GRO genes encoding cytokine functions. dans Proceedings of the National Academy of Sciences of the United States of America 1990
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Migration, invasion, proliferation and tube-formation capability of HTR-8/SVneo trophoblast cells transfected with siRNA-CXCL3 were suppressed by down-regulation of CXCL3, while those behaviors of HTR-8/SVneo cells transfected with pEZ-CXCL3 were enhanced by upregulation of CXCL3. Nevertheless, the apoptosis of HTR-8/SVneo cells was not affected by either siRNA or overexpression plasmid.
This report demonstrates that Cxcl3 induces the migration of normal and neoplastic cerebellar precursor cells (GCPs) from the surface to the internal part of the cerebellum, a region where the GCPs differentiate, thus exiting the neoplastic program. In this way Cxcl3 counteracts the growth of medulloblastoma, tumor of the cerebellum originating from the GCPs.
CXCL3 exerts its carcinogenic potential by directly and/or indirectly regulating the downstream signaling pathways and the expression of transcription factors in PCa.
The studies revealed that, although overall structural and oligomerization features of CXCL3 and CXCL2 are similar, prominent differences were observed in their surface characteristics, thus implicating a functional divergence.
Exogenous CXCL3 induced Erk1/2 and ETS1 phosphorylation and promoted CD133 expression.
Our findings suggest that CXCL3 and its receptor CXCR2 are overexpressed in prostate cancer cells, prostate epithelial cells and prostate cancer tissues, which may play multiple roles in prostate cancer progression and metastasis.
results support a functional role of CXCL3 in breast cancer metastasis and as a viable target for cancer therapy
CXCL3 displays antimicrobial activity against E. coli and S. aureus.
our results demonstrate the diverse mechanisms by which CXCL2 and CXCL3 mediate normal and asthmatic airway smooth muscle cell migration
secreted growth-regulated oncogene chemokines, specifically GRO-gamma, in human Mesenchymal stromal cell-conditioned media have an effect on the differentiation and the function of human monocyte-derived dendritic cells.
Data show that mesenchymal stem cells (MSCs) directly regulate T cell proliferation by induction of CXCL3 chemokine and its receptor, CXCR2 on the surface in T cells.
This study demonistrated that CXCL1, CXCL2, CXCL3, CXCL8, and CXCL11, absent from normal muscle fibers, were induced in DMD myofibers.
A significantly increased expression of GRO-2, GRO-3, and IL-8 in colon carcinoma as compared to normal tissue, is reported.
demonstrates, for the first time, that BIRC3 (anti-apoptotic protein), COL3A1 (matrix protein synthesis), and CXCL3 (chemokine) were up-regulated in the thrombin-stimulated human umbilical vein endothelial cells
GRO-gamma is a promising candidate for Th2-associated glomerular permeability factor in minimal change disease.
Inhibition of ERK phosphorylation decreased expression of GRO3.
Report gonadotropin-releasing hormone-regulated CXCL3 expression in human placentation.
propose that chemokines belonging to the CXC family could play an important role in the etiology of tendon xanthoma (TX), with CXCL3 being a possible biological marker of onset and development of TX
overexpression of CXCL13 in the intestine during inflammatory conditions favors mobilization of B cells and of LTi and NK cells with immunomodulatory and reparative functions.
CXCL3/GRO-gamma is the major chemotactic factor for neutrophils in bovine milk in the absence of inflammation, and that it is secreted constitutively in milk by mammary epithelial cells.
these results have indicated that CXCL3 is a novel adipokine that facilitates adipogenesis in an autocrine and/or a paracrine manner through induction of c/ebpb and c/ebpd.
Tis21 induces migration of cerebellar granule neuron precursor cells through Cxcl3, which may represent a novel target for medulloblastoma therapy
DCIP-1 interacts with chemokine CXCR2 and mediates human neutrophil chemotaxis, consistent with its role during the early proinflammatory phase of dendritic cell maturation.
acts as a chemoattractant for neutrophils\; involved in the inflammatory response
chemokine (C-X-C motif) ligand 3
, C-X-C motif chemokine 3
, chemokine CXCL3/GRO-GAMMA
, GRO3 oncogene
, MGSA gamma
, growth-regulated protein gamma
, macrophage inflammatory protein 2-beta
, melanoma growth stimulatory activity gamma
, epithelial cell inflammatory protein
, cytokine-induced neutrophil chemoattractant 2
, cytokine-induced neutrophil chemoattractant-2
, macrophage inflammatory protein 2-alpha/beta
, dendritic cell inflammatory protein 1