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anti-Human IL-10 Anticorps:
anti-Mouse (Murine) IL-10 Anticorps:
anti-Rat (Rattus) IL-10 Anticorps:
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Human Polyclonal IL-10 Primary Antibody pour WB - ABIN3042618
Presti, DOrazio, Labra, La Ferla, Mezzasalma, Bizzaro, Giardina, Michelotti, Tursi, Vassallo, Di Gennaro: Evaluation of the probiotic properties of new Lactobacillus and Bifidobacterium strains and their in vitro effect. dans Applied microbiology and biotechnology 2015
Show all 17 Pubmed References
Rat (Rattus) Polyclonal IL-10 Primary Antibody pour IHC (p), ELISA - ABIN3042802
Gao, Zhao, Liu, Yuan, Wu, Xia: Myocardial ischemic post-conditioning protects the lung against myocardial ischemia/reperfusion-induced damage by activating GSK-3β. dans Acta cirurgica brasileira 2017
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Mouse (Murine) Polyclonal IL-10 Primary Antibody pour ELISA, WB - ABIN3042803
Jin, Yang, Song, Zhang, Li: Protective roles of quercetin in acute myocardial ischemia and reperfusion injury in rats. dans Molecular biology reports 2012
Show all 14 Pubmed References
Human Monoclonal IL-10 Primary Antibody pour - ABIN1383949
Schandené, Alonso-Vega, Willems, Gérard, Delvaux, Velu, Devos, de Boer, Goldman: B7/CD28-dependent IL-5 production by human resting T cells is inhibited by IL-10. dans Journal of immunology (Baltimore, Md. : 1950) 1994
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Human Polyclonal IL-10 Primary Antibody pour IHC (p), ELISA - ABIN3042804
Wang, Lu, Zhang, Chen, Luo, Qin, Chen: Increased IL-10 mRNA expression in tumor-associated macrophage correlated with late stage of lung cancer. dans Journal of experimental & clinical cancer research : CR 2011
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Mouse (Murine) Polyclonal IL-10 Primary Antibody pour ELISA, WB - ABIN5692878
Zhang, Leng, Xue, Zhang, Wang, Kang: Effects of penehyclidine hydrochloride in small intestinal damage caused by limb ischemia-reperfusion. dans World journal of gastroenterology 2011
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Human Polyclonal IL-10 Primary Antibody pour ELISA, IF (p) - ABIN672051
Kou, Hu, Yao, Wang, Shen, Kang, Hong: Transforming growth factor-?1 promotes Treg commitment in nasal polyposis after intranasal steroid treatment. dans Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2013
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Human Monoclonal IL-10 Primary Antibody pour ICC - ABIN2689715
Abrams, Roncarolo, Yssel, Andersson, Gleich, Silver: Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples. dans Immunological reviews 1992
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Human Monoclonal IL-10 Primary Antibody pour ICS, Neut - ABIN1177280
Abrams: Immunoenzymetric assay of mouse and human cytokines using NIP-labeled anti-cytokine antibodies. dans Current protocols in immunology / edited by John E. Coligan ... [et al.] 2008
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Human Monoclonal IL-10 Primary Antibody pour ICS, Neut - ABIN1177281
Andersson, Christensen, Marker, Thomsen: Changes in cell adhesion molecule expression on T cells associated with systemic virus infection. dans Journal of immunology (Baltimore, Md. : 1950) 1994
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The authors found that CC genotype carriage may be associated with decreased risk of Ischemic Stroke in Chinese Han Population. IL-10 -819 C>T may be an independent protective factor for Ischemic Stroke in Han group.
Genetic relationship between IL-10 gene polymorphisms and the risk of clinical atopic dermatitis
These results indicate that functional lactic acid bacteria induce IL-6 and IL-10 production by dendritic cells, which contribute to upregulating the sIgA concentration at mucosal sites in humans.
rs1800896 not associated with recurrent pregnancy loss
The meta-analysis suggested that the mutation of IL-1beta(-511C/T) in Europe and IL-1beta(+3954C/T) in America tend to increase the risk of RAS, but the polymorphism of IL-10(-1082G/A) appears to have no association with RAS risk in America.
We provide the first ex vivo characterization of human intestinal type 1 regulatory T cells. Selective downregulation of IL-10 by IFN-gamma(+) TR1 cells in response to proinflammatory cytokines is likely to drive excessive intestinal inflammation in patients with inflammatory bowel diseases.
The expression of B7-H3 and B7-H4 favored an immunosuppressive microenvironment by promoting the production of IL-10 and TGFB1, thereby resulting in progression of cervical carcinogenesis.
IL-10 is an anti-inflammatory cytokine, and IL10 gene variants have been associated with cardiovascular disease and type 2 diabetes mellitus risk.
Niemann-Pick C1 protein (NPC1) gene expression showed positive significant correlation with interleukin 10 (IL-10) serum concentration.
This meta-analysis suggested that the IL10-1082 A > G polymorphism was associated with chronic periodontitis CP risk in non-Asians.
Modulation of CCL2 and IL-10.
Results provide evidence that SNPs in IL-10 (- 819 C/T, rs1800871) promoters were associated with a lower risk for gastric cancer in a Mexican population.
IL-10 gene polymorphisms are associated with IL-10 expression and the severity of EV71 infection in children
The frequency of IL-10-secreting B cells did not correlate with risk factors of MS.
All changes lead to further exacerbated colitis in IL10(-/-) mice with antibiotic treatment.
GMSCs play a critical role in alleviating colitis by modulating inflammatory immune cells via IL-10 signalling.
High IL10 expression is associated with postoperative complications in pancreatic, hepatic and gastric tumors.
No association with HTLV-1 infection was observed. However, allele A of rs1800896 (1082bp upstream) was associated with protection against neurological impairment, specifically overactive bladder (OR=0.447, 95% CI 0.28-0.70, p=0.001).
There is a significant correlation between IL-6 and IL-10 levels and serum bicarbonate and the incidence of metabolic acidosis in hemodialysis patients.
Letter: The cytokine IL-10 is an indicator rather than a mediator of rejection which can be induced to a greater extent by an active rejection process and a lesser extent by an incompletely suppressed immune reaction in kidney transplant recipients.
The data demonstrate that endogenous IL-10 is critical in the maintenance of immune tolerance but exogenous administration of IL-10 exacerbates liver inflammation and fibrosis.
Infiltrating monocytes were identified as main IL-10 producers.
Results provide evidence that PIBF containing extracellular vesicles from mouse embryos alter IL-10 expression of mouse peripheral lymphocytes.
IL10 may be essential in lenalidomide-ameliorated experimental autoimmune encephalomyelitis.
Findings reveal a critical role for ADRB2 signaling in controlling inflammation through the rapid induction of IL-10. Findings provide a fundamental insight into how the sympathetic nervous system controls a critical facet of immune function through ADRB2 signaling.
Our data, therefore, establish that IL-10 signaling can directly control Th17 differentiation in CD4+ T cells via the IL-10Ra.
This effect is associated with an increased population of IL-10-secreting immune cells.
this paper shows that autocrine IL-10 signaling promotes dendritic cell type-2 activation and persistence of murine cryptococcal lung infection
RFlaA:Betv1-mediated IL-10 secretion.
Both IL-6 and IL-10 can activate S100A9 expression.
B cells are related with lesion pathogenesis through the production of antibodies and IL-10.
Our data indicate that a defective IL-10 production contributes to the pathogenesis of systemic juvenile idiopathic arthritis
Loss of interleukin 10 (IL10) expression in transgenic mice expressing catalytically inactive RAG1 (dnRAG) mice had no significant effect on B10-like B cell expansion.
Bhlhe40 is required to repress Il10 expression during Mycobacterium tuberculosis infection.
these findings demonstrate that IL-10 is pivotal to prevent gluten-induced small intestinal inflammation and epithelial damage
This study demonstrated that astrocyte-targeted IL-10 production induces significant changes in the activation pattern of microglia/macrophage cell population after transection of perforant pathway.
These data suggest a potent regulatory role of IL-10 in the cross-reactive memory response to the infection with heterologous Plasmodium parasites leading to the inhibition of the protective immunity and pathogenesis.
B cells are the major producers of IL-10 in-vivo. In regulatory B cells, BATF, IFN regulatory factor, and IRF-8 transcription factors were recruited and bound to AP1-IRF-composite elements of il12a, ebi3, and/or il10 loci.
IL-10 can directly alter gonadotropin-releasing hormone neuron firing and induce ERK1/2 phosphorylation
Incorporation of IL-10 blocking agents may enhance current therapeutic regimens for CLL by potentiating host antitumor immune response.
Studied expression of Interleukin 10 (IL-10) in blood and milk samples of 25 healthy and 25 mastitic cows. Found IL-10 expression to be significantly higher in the blood and milk samples of mastitic cows compared to the healthy ones.
This study seems to indicate that PGE2 in cattle does not produce an anti-inflammatory effect by increasing the synthesis of IL-10.
IL-10 mRNA expression increased on day 8 in the mononuclear leukocytes of pregnant cows. In a cell culture experiment, interferon-tau stimulated stimulated IL-10 mRNA expression in mononuclear leukocytes.
Bovine IL-10 potently inhibits the activation of human myeloid cells in response to toll like receptor activation.
Levels in milk are altered in the presence of bacteria.
Monocytes obtained from cows with subclinical infection with MAP had upregulated expression of IL-10 and SOCS-3, which may have attenuated the capacity of mononuclear phagocytes to initiate inflammatory and adaptive immune responses.
The ability of an EHV-1 isolate to down-regulate IL-10 production might contribute to increased local inflammation and a higher risk for neurological manifestation of the disease after infection with Ab4.
The data suggested in foals there is an impaired Th2 response, the immune response is Th1 biased, interferon-gamma production is qualitatively similar to adult horses, and regulatory IL-10 production by T cells is mature.
serum IL-6:IL-10 ratio is likely to provide a valuable prognosticator for neonatal septicemia
The effect of clenbuterol on cytokine metabolism in the peripheral white blood cells in those horses with small airway diseases that have been exposed to lipopolysaccharides is reported.
The contribution of bronchial epithelium to airway inflammation, with focus on mRNA and protein expression of IL-6, IL-10 and TNF-alpha, in horses with recurrent airway obstruction during exacerbation and in remission is reported.
The complete open reading frame consists of 537 base pairs which encodes a protein of 179 amino acids. This cDNA sequence exhibited 87% homology with human IL-10.
Single nucleotide polymorphisms on exon 3 were significantly associated with immune traits.
ICAM1 and IL10 were upregulated in ventilator-induced lung injury. Nuclear transcription factor AP-1 may be responsible for this upregulation.
In contrast to lung tissue, in which Actinobacillus pleuropneumoniae (APP) presence was associated with a pronounced pro-inflammatory character, APP presence in the tonsils elicited an increased IL-10 expression.
The PRRSV vaccination induced higher levels of IL-10 expression in the first week and this may be why the CSFV vaccination is immunosuppressed.
These data indicate that the type 2 porcine reproductive and respiratory syndrome virus N protein plays an important role in IL-10 induction and the N-N non-covalent domain is associated with this activity.
The effects of semen, spermatozoa in extender, or extender alone on the expression of TGF-beta1, IL-10, and IL-6 in ovarian follicles are reported.
Prostaglandin E2 potentiates mesenchymal stem cell-induced IL-10+IFN-gamma+CD4+ regulatory T cells to control transplant arteriosclerosis.
Porcine reproductive and respiratory syndrome virus strain CH-1a could significantly up-regulate IL-10 production through p38 MAPK activation.
Boar seminal plasma contained TGF- beta1 and IL-10 but with high individual variation.
Changes in interleukin-10 mRNA expression are predictive for 9-day survival of pigs in an emergency preservation and resuscitation model.
These results suggest that TNF-alpha and IL-10, but not IL-6, are involved in the late reparatory phases of the experimental disk lesion.
The present study shows that elevated levels of serum CRP and IL-10 were associated with porcine circovirus type 2-infected piglets that subsequently developed severe PMWS.(postweaning multisystemic wasting syndrome)
Subclinically porcine circovirus type 2 (PCV2)-infected pigs developed a transient PCV2-specific IL-10 response during the viremic phase of infection which coincided with the inversion of the IgM/IgG ratio.
Twenty one polymorphisms in the IL10 gene have been found, including single nucleotide polymorphisms and insertion deletion polymorphisms. The chromosomal location has been mapped by FISH and radiation hybrid mapping.
findings show that Brachyspira hyodysenteriae inoculation induced production of systemic levels of IL-1beta during the dysentery period and increased levels of IL-10 coincided with recovery from dysentery
IL-10 produced during the immune response to malaria in this model contributes to suppression of mucosal inflammatory responses to invasive NTS, which may contribute to differences in the clinical presentation of NTS infection in the setting of malaria.
Findings demonstrate that internalization of IL-10R with the resultant impact on IL-10 signaling and dysregulation of the IL-10-mediated anti-inflammatory responses might play a crucial role in epithelial cell damage and subsequent simian immunodeficiency virus pathogenesis.
IL-10 plays a crucial role in maintaining mucosal homeostasis by regulating mucosal IFNgamma and TNFalpha cytokine production.
The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.
T-cell growth inhibitory factor
, cytokine synthesis inhibitory factor
, uncharacterized protein LOC100715618
, Cytokine synthesis inhibitory factor