Profil protéine

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with LILRB2

• leukocyte immunoglobulin-like receptor subfamily A member 3 (LOC100433990) anticorps
• leukocyte immunoglobulin like receptor B2 (LILRB2) anticorps

• CD85D anticorps
• ILT-4 anticorps
• ILT4 anticorps
• LIR-2 anticorps
• LIR2 anticorps
• Afficher tous les alias de synonymes
• MIR-10 anticorps
• MIR10 anticorps

Protein level used designations for LILRB2

leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 , leukocyte immunoglobulin-like receptor subfamily B member 2-like , CD85 antigen-like family member D , Ig-like transcript 4 , leukocyte immunoglobulin-like receptor subfamily B member 2 , monocyte/macrophage immunoglobulin-like receptor 10