anti-Chien AIRE anticorps pour Enzyme Immunoassay

Recommended AIRE Antibody (fourni par: Connectez-vous pour afficher )

Antigène
Autoimmune Regulator (AIRE) Anticorps
  • AIRE1
  • APECED
  • APS1
  • APSI
  • PGA1
  • autoimmune regulator
  • autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)
  • AaeL_AAEL013794
  • CpipJ_CPIJ001208
  • CpipJ_CPIJ001209
  • AIRE
  • Aire
Épitope
Internal Region, Isoform 1
37
19
16
12
11
7
5
4
4
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivité
Chien, Humain, Rat (Rattus)
166
74
29
10
9
8
6
4
4
2
1
Hôte
Chèvre
114
59
10
1
1
Clonalité
Polyclonal
Conjugué
Cet anticorp AIRE est non-conjugé
7
6
6
6
5
5
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
162
103
50
39
16
15
11
11
5
4
4
2
1
1
1
Fournisseur
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N° du produit (Fournisseur)
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N° du produit ABIN5553212
$ 462.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
1 ABIN372242 EIA IHC (p) WB Goat IgG Internal Region Connectez-vous pour afficher Polyclonal 0

General

Antigène Autoimmune Regulator (AIRE) Anticorps
Épitope Internal Region, Isoform 1
(37), (19), (16), (12), (11), (7), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivité Chien, Humain, Rat (Rattus)
(166), (74), (29), (10), (9), (8), (6), (4), (4), (2), (1)
Hôte Chèvre
(114), (59), (10), (1), (1)
Clonalité
Polyclonal
Conjugué Cet anticorp AIRE est non-conjugé
(7), (6), (6), (6), (5), (5), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(162), (103), (50), (39), (16), (15), (11), (11), (5), (4), (4), (2), (1), (1), (1)
Fournisseur Connectez-vous pour afficher

Détail du produit anti-AIRE anticorps

Détail du antigène AIRE Information d'application Stockage Images
Séquence C-KDVDLSQPRK GRKP
Specificité This antibody is expected to recognise isoform 1 (NP_000374.1) only.
Réactivité croisée (Details) Species reactivity (expected):Rat, Canine and Cow.
Species reactivity (tested):Human.
Purification Ammonium sulphate precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
Immunogène Peptide with sequence from the internal region of the protein sequence according to NP_000374.1.
Plasmids, Primers & others

Détail du antigène AIRE

Détail du produit anti-AIRE anticorps Information d'application Stockage Images Haut de la page
Antigène
Autre désignation AIRE / APECED (AIRE Antibody Extrait)
Sujet AIRE is a transcriptional regulator that is thought to be important in controlling tissue-specific expression of genes in the thymus. The precise function of the protein is not well defined. It contains zinc finger motifs and isoform 1 is localized to both the nucleus and cytoplasm. Three splice variant mRNAs products have been described. The longer AIRE1 mRNA appears to be more abundant and includes exons 1 through 14. Splice variant AIRE2 includes a portion of the non-coding region of exon 1, an alternatively spliced longer exon 8, plus exons 9 through 14. Variant AIRE3 includes the same exon 1-8-9 sequences as found in AIRE2 but utilizes additional alternative splicing in exon 10 that shifts the reading frame such that a stop codon in exon 12 is utilized. The resulting protein products of these splice variants differ significantly. Defects in this gene cause the autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED).Synonyms: Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein, Autoimmune regulator
ID gène 326, 9606
UniProt O43918
Pathways Chromatin Binding

Information d'application

Détail du produit anti-AIRE anticorps Détail du antigène AIRE Stockage Images Haut de la page
Indications d'application Peptide ELISA: 1/32000. Western blot: 0.5-1.0 μg/mL. Immunohistochemistry: 2.5 μg/mL. In paraffin embedded Human Thymus shows nuclear staining in select thymocytes.
Restrictions For Research Use only

Stockage

Détail du produit anti-AIRE anticorps Détail du antigène AIRE Information d'application Images Haut de la page
Concentration 0.5 mg/mL
Buffer Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freezing and thawing.
Stock 4 °C/-20 °C
Stockage commentaire Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C.