anti-Chien TFAM anticorps pour Western Blotting

Recommended TFAM Antibody (fourni par: Connectez-vous pour afficher )

Antigène
Transcription Factor A, Mitochondrial (TFAM) Anticorps
  • tcf6
  • mttf1
  • mttfa
  • tcf6l1
  • tcf6l2
  • tcf6l3
  • mttfa-A
  • xl-mtTFA
  • MGC153358
  • zgc:153358
  • MTTF1
  • MTTFA
  • TCF6
  • TCF6L1
  • TCF6L2
  • TCF6L3
  • AI661103
  • Hmgts
  • mtTFA
  • tsHMG
  • Mttfa
  • transcription factor A, mitochondrial
  • transcription factor A, mitochondrial L homeolog
  • TFAM
  • tfam.L
  • tfam
  • Tfam
Épitope
N-Term
18
11
9
9
8
6
6
6
5
4
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Reactivité
Boeuf (Vache), Chien, Cobaye, Cheval, Humain, Souris, Porc, Lapin
136
58
51
4
2
1
1
Hôte
Lapin
147
22
Clonalité
Polyclonal
Conjugué
Cet anticorp TFAM est non-conjugé
10
10
5
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
136
98
64
50
45
38
20
15
14
13
4
3
2
2
Options
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N° du produit ABIN2777277
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
1 ABIN214152 IHC IHC (p) WB Rabbit IgG AA 75-124 Connectez-vous pour afficher Polyclonal 0

General

Antigène Transcription Factor A, Mitochondrial (TFAM) Anticorps
Épitope N-Term
(18), (11), (9), (9), (8), (6), (6), (6), (5), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivité Boeuf (Vache), Chien, Cobaye, Cheval, Humain, Souris, Porc, Lapin
(136), (58), (51), (4), (2), (1), (1)
Hôte Lapin
(147), (22)
Clonalité
Polyclonal
Conjugué Cet anticorp TFAM est non-conjugé
(10), (10), (5), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Western Blotting (WB)
(136), (98), (64), (50), (45), (38), (20), (15), (14), (13), (4), (3), (2), (2)
Pubmed 10 références disponible
Fournisseur Connectez-vous pour afficher

Détail du produit anti-TFAM anticorps

Détail du antigène TFAM Information d'application Stockage References for anti-TFAM antibody (ABIN2777277) Images
Blocking Peptide Blocking peptide for this product available: ABIN984969
Séquence AKTTELIRRI AQRWRELPDS KKKIYQDAYR AEWQVYKEEI SRFKEQLTPS
Homologie Cow: 92%, Dog: 83%, Guinea Pig: 75%, Horse: 92%, Human: 100%, Mouse: 75%, Pig: 92%, Rabbit: 83%
Attributs du produit This is a rabbit polyclonal antibody against Transcription Factor AntibodiesAM. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogène The immunogen is a synthetic peptide directed towards the N terminal region of human TFAM
Plasmids, Primers & others

Détail du antigène TFAM

Détail du produit anti-TFAM anticorps Information d'application Stockage References for anti-TFAM antibody (ABIN2777277) Images Haut de la page
Antigène
Autre désignation TFAM (TFAM Antibody Extrait)
Sujet The function remains unknown.This gene encodes a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this gene product is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns-Sayre syndrome was produced when expression of this gene was eliminated by targeted disruption in heart and muscle cells.
Alias Symbols: TCF6, MtTF1, mtTFA, TCF6L1, TCF6L2, TCF6L3
Protein Interaction Partner: AGTRAP, FBXW11, ARL6IP1, NEDD1, PPP2R1A, GRSF1, UBC, MDM2, SUZ12, EED, PAN2, MYC, FN1, C1QBP, CAND1, COPS5, CUL3, ELAVL1, ICT1, TFB2M, TFB1M, PNP, NRF1,
Protein Size: 246
Poids moléculaire 29 kDa
ID gène 7019
NCBI Accession NM_003201, NP_003192
UniProt Q00059
Pathways Chromatin Binding

Information d'application

Détail du produit anti-TFAM anticorps Détail du antigène TFAM Stockage References for anti-TFAM antibody (ABIN2777277) Images Haut de la page
Indications d'application Optimal working dilutions should be determined experimentally by the investigator.
Commentaires

Antigen size: 246 AA

Restrictions For Research Use only

Stockage

Détail du produit anti-TFAM anticorps Détail du antigène TFAM Information d'application References for anti-TFAM antibody (ABIN2777277) Images Haut de la page
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freeze-thaw cycles.
Stock -20 °C
Stockage commentaire For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-TFAM antibody (ABIN2777277)

Détail du produit anti-TFAM anticorps Détail du antigène TFAM Information d'application Stockage Images Haut de la page
Produit citée dans:

Ogasawara, Liu, Pelicano, Hammoudi, Croce, Keating, Huang: "Alterations of mitochondrial biogenesis in chronic lymphocytic leukemia cells with loss of p53." dans: Mitochondrion, Vol. 31, pp. 33-39, 2016

Kemper, Stirone, Krause, Duckles, Procaccio: "Genomic and non-genomic regulation of PGC1 isoforms by estrogen to increase cerebral vascular mitochondrial biogenesis and reactive oxygen species protection." dans: European journal of pharmacology, Vol. 723, pp. 322-9, 2014

Vettor, Valerio, Ragni, Trevellin, Granzotto, Olivieri, Tedesco, Ruocco, Fossati, Fabris, Serra, Carruba, Nisoli: "Exercise training boosts eNOS-dependent mitochondrial biogenesis in mouse heart: role in adaptation of glucose metabolism." dans: American journal of physiology. Endocrinology and metabolism, Vol. 306, Issue 5, pp. E519-28, 2014

Kemper, Zhao, Duckles, Krause: "Endogenous ovarian hormones affect mitochondrial efficiency in cerebral endothelium via distinct regulation of PGC-1 isoforms." dans: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 33, Issue 1, pp. 122-8, 2013

Teodoro, Duarte, Gomes, Varela, Peixoto, Rolo, Palmeira: "Berberine reverts hepatic mitochondrial dysfunction in high-fat fed rats: a possible role for SirT3 activation." dans: Mitochondrion, Vol. 13, Issue 6, pp. 637-46, 2013

Miyazaki, Iwasawa, Nakashima, Mori, Shigemoto, Nakamura, Katagiri, Takayanagi, Tanaka: "Intracellular and extracellular ATP coordinately regulate the inverse correlation between osteoclast survival and bone resorption." dans: The Journal of biological chemistry, Vol. 287, Issue 45, pp. 37808-23, 2012

Lu, Chen, Zhang, Wang, Luo, Huang: "ZNF143 transcription factor mediates cell survival through upregulation of the GPX1 activity in the mitochondrial respiratory dysfunction." dans: Cell death & disease, Vol. 3, pp. e422, 2012

Walters, Wallace: "Urea cycle gene expression is suppressed by PFOA treatment in rats." dans: Toxicology letters, Vol. 197, Issue 1, pp. 46-50, 2010

Walters, Bjork, Wallace: "Perfluorooctanoic acid stimulated mitochondrial biogenesis and gene transcription in rats." dans: Toxicology, Vol. 264, Issue 1-2, pp. 10-5, 2009

Shi, Burkart, Nicoloro, Czech, Straubhaar, Corvera: "Paradoxical effect of mitochondrial respiratory chain impairment on insulin signaling and glucose transport in adipose cells." dans: The Journal of biological chemistry, Vol. 283, Issue 45, pp. 30658-67, 2008

Images

Détail du produit anti-TFAM anticorps Détail du antigène TFAM Information d'application Stockage References for anti-TFAM antibody (ABIN2777277) Haut de la page
Images (Fournisseur)
Western Blotting (WB) image for anti-Transcription Factor A, Mitochondrial (TFAM) (N-Term) antibody (ABIN2777277) anti-Transcription Factor A, Mitochondrial (TFAM) (N-Term) antibody
Western Blotting (WB) image for anti-Transcription Factor A, Mitochondrial (TFAM) (N-Term) antibody (ABIN2777277) anti-Transcription Factor A, Mitochondrial (TFAM) (N-Term) antibody (Image 2)
Western Blotting (WB) image for anti-Transcription Factor A, Mitochondrial (TFAM) (N-Term) antibody (ABIN2777277) Lanes: Lane 1 and 2: HepG2 cell lysate Lane 3 and 4: Hep3B cell lysate Lane 5 and 6...
Western Blotting (WB) image for anti-Transcription Factor A, Mitochondrial (TFAM) (N-Term) antibody (ABIN2777277) TFAM antibody - N-terminal region validated by WB using bEND3 cell lysate at lane1:1...
Western Blotting (WB) image for anti-Transcription Factor A, Mitochondrial (TFAM) (N-Term) antibody (ABIN2777277) WB Suggested Anti-TFAM Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Pos...
Western Blotting (WB) image for anti-Transcription Factor A, Mitochondrial (TFAM) (N-Term) antibody (ABIN2777277) TFAM antibody - N-terminal region validated by WB using bEND3 cell lysate at lane1:1...