anti-Humain TFAM anticorps pour Immunohistochemistry (Frozen Sections)

Recommended TFAM Antibody (fourni par: Connectez-vous pour afficher )

Antigène
Transcription Factor A, Mitochondrial (TFAM) Anticorps
  • tcf6
  • mttf1
  • mttfa
  • tcf6l1
  • tcf6l2
  • tcf6l3
  • mttfa-A
  • xl-mtTFA
  • MGC153358
  • zgc:153358
  • MTTF1
  • MTTFA
  • TCF6
  • TCF6L1
  • TCF6L2
  • TCF6L3
  • AI661103
  • Hmgts
  • mtTFA
  • tsHMG
  • Mttfa
  • transcription factor A, mitochondrial
  • transcription factor A, mitochondrial L homeolog
  • TFAM
  • tfam.L
  • tfam
  • Tfam
Épitope
AA 227-246, C-Term
16
11
9
8
8
6
6
6
5
4
3
3
2
2
2
1
1
1
1
1
1
1
1
Reactivité
Humain
131
55
52
5
3
2
2
1
1
Hôte
Lapin
145
19
Clonalité
Polyclonal
Conjugué
Cet anticorp TFAM est non-conjugé
10
10
5
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
132
93
60
49
40
34
19
15
14
13
4
2
2
2
Options
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N° du produit ABIN3044014
$ 280.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
10 ABIN3029197 ICC IHC (fro) IHC (p) WB Rabbit IgG C-Term Connectez-vous pour afficher Polyclonal 0
1 ABIN2625799 ICC IHC IHC (fro) IHC (p) WB Rabbit IgG AA 227-246 Connectez-vous pour afficher Polyclonal 0

General

Antigène Transcription Factor A, Mitochondrial (TFAM) Anticorps
Épitope AA 227-246, C-Term
(16), (11), (9), (8), (8), (6), (6), (6), (5), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivité Humain
(131), (55), (52), (5), (3), (2), (2), (1), (1)
Hôte Lapin
(145), (19)
Clonalité
Polyclonal
Conjugué Cet anticorp TFAM est non-conjugé
(10), (10), (5), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(132), (93), (60), (49), (40), (34), (19), (15), (14), (13), (4), (2), (2), (2)
Pubmed 1 référence disponible
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Détail du produit anti-TFAM anticorps

Détail du antigène TFAM Information d'application Stockage References for anti-TFAM antibody (ABIN3044014) Images
Fonction Rabbit IgG polyclonal antibody for Transcription factor A, mitochondrial(TFAM) detection. Tested with WB, IHC-P, IHC-F, ICC in Human.
Séquence RKDLLRRTIK KQRKYGAEEC
Réactivité croisée (Details) No cross reactivity with other proteins.
Attributs du produit Rabbit IgG polyclonal antibody for Transcription factor A, mitochondrial(TFAM) detection. Tested with WB, IHC-P, IHC-F, ICC in Human.
Gene Name: transcription factor A, mitochondrial
Protein Name: Transcription factor A, mitochondrial
Purification Immunogen affinity purified.
Immunogène A synthetic peptide corresponding to a sequence at the C-terminus of human mtTFA(227-246aa RKDLLRRTIKKQRKYGAEEC).
Isotype IgG
Plasmids, Primers & others

Détail du antigène TFAM

Détail du produit anti-TFAM anticorps Information d'application Stockage References for anti-TFAM antibody (ABIN3044014) Images Haut de la page
Antigène
Autre désignation TFAM (TFAM Antibody Extrait)
Sujet TFAM(Transcription factor A, mitochondrial), also known as TCF6 or TCF6L2, is a 162-amino acid protein that activates transcription of each mitochondrial DNA(mtDNA) strand by binding to an element of approximately 30 nucleotides present in both the light-strand and the heavy-strand promoters. By Southern blot analysis of restriction enzyme digests of human/Chinese hamster somatic cell hybrid lines, Milatovich et al.(1992) mapped TFAM sequences, which they called MTTF1, to 3 different chromosomes: chromosomes 10, 7p, and 11q. By PCR-based screening of a somatic cell hybrid panel and by fluorescence in situ hybridization, Scott(2007) stated that the sequences mapped to chromosomes 7p(TCF6L1) and 11q(MTTF1, or TCF6L3) are pseudogenes. Larsson et al.(1997) mapped the mouse mitochondrial transcription factor A gene(Tfam) to the central part of mouse chromosome 10. This region exhibits syntenic homology with human 10q21. Mitochondrial transcription factor A is a key activator of mitochondrial transcription in mammals. It also has a role in mitochondrial DNA replication, since transcription generates an RNA primer necessary for initiation of mtDNA replication.

Synonyms: anscription factor 6-like 1 antibody|Mitochondrial transcription factor 1 antibody|mitochondrial transcription factor A antibody|MtTF1 antibody|mtTFA antibody|TCF 6 antibody|TCF-6 antibody|TCF6 antibody|TCF6L1 antibody|TCF6L2 antibody|TCF6L3 antibody|TFAM antibody|TFAM_HUMAN antibody|Transcription factor 6 antibody|Transcription factor 6 like 2(mitochondrial transcription factor) antibody|Transcription factor 6 like 2 antibody|Transcription factor 6-like 2 antibody|transcription factor 6-like 3 antibody|Transcription factor A, mitochondrial antibody|Transcription factor A, mitochondrial precursor antibody
UniProt Q00059
Pathways Chromatin Binding

Information d'application

Détail du produit anti-TFAM anticorps Détail du antigène TFAM Stockage References for anti-TFAM antibody (ABIN3044014) Images Haut de la page
Indications d'application WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Human
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Commentaires

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC.

Restrictions For Research Use only

Stockage

Détail du produit anti-TFAM anticorps Détail du antigène TFAM Information d'application References for anti-TFAM antibody (ABIN3044014) Images Haut de la page
Format Lyophilized
Reconstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Concentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
Agent conservateur Thimerosal (Merthiolate), Sodium azide
Précaution d'utilisation This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freezing and thawing.
Stock 4 °C/-20 °C
Stockage commentaire At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Date de péremption 12 months

References for anti-TFAM antibody (ABIN3044014)

Détail du produit anti-TFAM anticorps Détail du antigène TFAM Information d'application Stockage Images Haut de la page
Produit citée dans:

Wu, Zhao, Xiao, Peng, Chen, He: "Roles of mitochondrial transcription factor A and microRNA‑590‑3p in the development of colon cancer." dans: Molecular medicine reports, Vol. 14, Issue 6, pp. 5475-5480, 2017

Images

Détail du produit anti-TFAM anticorps Détail du antigène TFAM Information d'application Stockage References for anti-TFAM antibody (ABIN3044014) Haut de la page
Images (Fournisseur)
Immunohistochemistry (IHC) image for anti-Transcription Factor A, Mitochondrial (TFAM) (AA 227-246), (C-Term) antibody (ABIN3044014) Anti-mtTFA antibody, ICC ICC: HELA Cell
Western Blotting (WB) image for anti-Transcription Factor A, Mitochondrial (TFAM) (AA 227-246), (C-Term) antibody (ABIN3044014) Lane 9: HUT Cell Lysate
Immunohistochemistry (IHC) image for anti-Transcription Factor A, Mitochondrial (TFAM) (AA 227-246), (C-Term) antibody (ABIN3044014) Anti-mtTFA antibody, IHC(P) IHC(P): Human Intestinal Cancer Tissue
Immunohistochemistry (IHC) image for anti-Transcription Factor A, Mitochondrial (TFAM) (AA 227-246), (C-Term) antibody (ABIN3044014) Anti-mtTFA antibody, IHC(F) IHC(F): Human Placenta Tissue
 image for anti-Transcription Factor A, Mitochondrial (TFAM) (AA 227-246), (C-Term) antibody (ABIN3044014) Western blot analysis of mtTFA using anti- mtTFA antibody . Electrophoresis was perf...