Catechol-O-Methyltransferase Produits
(Catechol-O-Methyltransferase (COMT))
Catégories
Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters. [provided by RefSeq, Sep 2008].
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Catégories Catechol-O-Methyltransferase en vedette
Catechol-O-Methyltransferase Anticorps
High quality antibodies with extensive validation data.
Catechol-O-Methyltransferase Kits ELISA
Reliable ELISA kits for a wide range of species.
Catechol-O-Methyltransferase Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Catechol-O-Methyltransferase recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (6)
N° du produit
ABIN185682
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (1)
- (4)
N° du produit
ABIN2854980
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, FACS
Validations
- (5)
N° du produit
ABIN185328
Quantité
100 μg
Fiche technique
Fiche technique
Catechol-O-Methyltransferase recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6954432
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6954433
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6954434
Quantité
96 tests
Fiche technique
Fiche technique
Catechol-O-Methyltransferase recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7122177
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1350032
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN666744
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Catechol-O-Methyltransferase
: "m6A Demethylase FTO Regulates Dopaminergic Neurotransmission Deficits Caused by Arsenite." dans: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 165, Issue 2, pp. 431-446, (2018) (PubMed).: "Inhibitory Effect of Bovine Lactoferrin on Catechol-O-Methyltransferase." dans: Molecules (Basel, Switzerland), Vol. 22, Issue 8, (2018) (PubMed).
: "Activation of the enzymes of phase I (CYP2B1/2) and phase II (SULT1A and COMT) metabolism by 2,2',4,4'-tetrabromodiphenyl ether (BDE47) in the pig ovary." dans: Reproductive toxicology (Elmsford, N.Y.), Vol. 34, Issue 3, pp. 436-42, (2012) (PubMed).
: "Intrarenal dopamine modulates progressive angiotensin II-mediated renal injury." dans: American journal of physiology. Renal physiology, Vol. 302, Issue 6, pp. F742-9, (2012) (PubMed).
: "Disturbed expression of phase I and phase II estrogen-metabolizing enzymes in endometrial cancer: lower levels of CYP1B1 and increased expression of S-COMT." dans: Molecular and cellular endocrinology, Vol. 331, Issue 1, pp. 158-67, (2010) (PubMed).
: "Chiral Brønsted acid catalyzed enantioselective addition of alpha-isocyanoacetamides to aldehydes." dans: Organic letters, Vol. 12, Issue 10, pp. 2414-7, (2010) (PubMed).
: "Impact of aerobic exercise training on cognitive functions and affect associated to the COMT polymorphism in young adults." dans: Neurobiology of learning and memory, Vol. 94, Issue 3, pp. 364-72, (2010) (PubMed).
: "Genetic polymorphism of catechol-O-methyltransferase and cytochrome P450c17α in preeclampsia." dans: Pharmacogenetics and genomics, Vol. 20, Issue 10, pp. 605-10, (2010) (PubMed).
: "Association between Novelty Seeking of opiate-dependent patients and the catechol-O-methyltransferase Val(158)Met polymorphism." dans: Comprehensive psychiatry, Vol. 51, Issue 5, pp. 510-5, (2010) (PubMed).
: "Effects of modafinil on the sleep EEG depend on Val158Met genotype of COMT." dans: Sleep, Vol. 33, Issue 8, pp. 1027-35, (2010) (PubMed).
Synonymes et noms alternatifs relatifs à Catechol-O-Methyltransferase
catechol-O-methyltransferase (COMT), catechol-O-methyltransferase (Comt), microRNA 4761 (MIR4761), catechol-O-methyltransferase (comt), catechol-O-methyltransferase (comt.2), catechol-O-methyltransferase S homeolog (comt.S), methyltransferase (Rv1703c), catechol-o-methyltransferase (Mb1729c), catechol-O-methyltransferase a (comta), catechol-O-methyltransferase b (comtb), catechol O-methyltransferase (LOC100354142), COMT, comt, Comt1, D16Wsu103e, D330014B15Rik, mb-comt, MGC154444, s-comt, si:dkey-13a21.15, zgc:114157, zgc:162236, zK13A21.15Protein level used designations for Catechol-O-Methyltransferase
- catechol O-methyltransferase
- catechol-O-methyltransferase 1
- catecholamine-O-methyltransferase
- catechol-O-methyltransferase
- O-methyltransferase
- catechol-o-methyltransferase
- catechol O-methyltransferase, soluble form
- catechol O-methyltransferase, membrane-bound form
- catechol-O-methyltransferase a
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