Aperçu des produits pour SSH1 Protéines (SSH1)

Mouse (Murine) Slingshot Homolog 1 (Drosophila) (SSH1) interaction partners

1. Caspase-11 (Montrer CASP4 Protéines) targets cofilin (Montrer CFL1 Protéines) via the RhoA GTPase, whereas caspase-1 (Montrer CASP1 Protéines) engages the Slingshot phosphatase

2. SSH1L knockdown, like S1P (Montrer S1PR1 Protéines) treatment, increased cardiomyocyte survival and preserved mitochondrial integrity after oxidative stress

3. EphA signaling promotes actin-based dendritic spine remodeling through slingshot 1.

4. PDGF (Montrer PDGFA Protéines) activates SSH1L in VSMC by a mechanism that involves Nox1 (Montrer NOX1 Protéines)-mediated oxidation of 14-3-3 (Montrer YWHAQ Protéines) and Ser (Montrer SIGLEC1 Protéines)-834 SSH1L auto-dephosphorylation.

5. Knockdown of SSH1 expression by RNA interference significantly suppressed stress fiber formation in C2C12 myoblast cells, indicating a role for SSH1 in stress fiber formation or stabilization in cells.

Human Slingshot Homolog 1 (Drosophila) (SSH1) interaction partners

1. SSH1 binds to gelsolin (Montrer GSN Protéines) via actin filaments in the cytosolic fraction. Gelsolin (Montrer GSN Protéines) promoted solubilization of actin filaments and SSH1 in cell-free assays and in cultured cells.

2. the N-terminal PH-like domain plays a critical role in F-actin binding and F-actin-mediated activation of the cofilin (Montrer CFL1 Protéines)-phosphatase activity of SSH1

3. Results reveal that SSH1L is upregulated in a subset of PCs and that the SSH1L/cofilin-1 (Montrer CFL1 Protéines) signal pathway is associated positively in PC with cell migration.

4. Authors show that viral penetration-induced calcium release facilitated herpes simplex virus type 1 intracellular trafficking through activating slingshot 1 (SSH), a phosphatase regulating actin filament dynamics.

5. The association of IRS4 (Montrer IRS4 Protéines) with SSH1 contributes to localized activation of cofilin (Montrer CFL1 Protéines) in membrane protrusions.

6. Slingshot 1 downregulation in neuronal cells inactivates cofilin (Montrer CFL1 Protéines) to facilitate HSV-1 replication.

7. Thus this study provides evidence for a novel role of LIMK1 (Montrer LIMK1 Protéines) and SSH-1L in selectively regulating endothelial cell inflammation associated with intravascular coagulation.

8. Our work provides evidence that supports the positive role of SSH1L in the mechanism of stem cell differentiation into cardiomyocyte-like cells.

9. A high expression of SSH-1L in peripheral eosinophils in acute exacerbations of asthma may play a role in the activation and migration of eosinophils.

10. EphA signaling promotes actin-based dendritic spine remodeling through slingshot 1.