BRCA1 Protéines
10 Breast Cancer 1 (BRCA1) Protéines de 6 fabricants sont disponibles sur www.anticorps-enligne.fr.
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Breast Cancer 1 (BRCA1) Protéine Protein
Breast Cancer 1 (BRCA1) (AA 1-59) protein (GST tag) Protein
Breast Cancer 1 (BRCA1) (AA 1581-1670) protein (GST tag) Protein
Breast Cancer 1 (BRCA1) (AA 1524-1781) protein (His tag,T7 tag) Protein
Breast Cancer 1 (BRCA1) (AA 1579-1811) protein (His tag,GST tag) Protein
Breast Cancer 1 (BRCA1) (AA 19-83) protein (His tag) Protein
Breast Cancer 1 (BRCA1) Protéine Protein
Breast Cancer 1 (BRCA1) Protéine Protein
Breast Cancer 1 (BRCA1) protein (His tag) Protein
Breast Cancer 1 (BRCA1) Protéine Protein
Profil protéine BRCA1
Profil protéine
This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described. A related pseudogene, which is also located on chromosome 17, has been identified.
Alternative names and synonyms associated with BRCA1
- BRCA1, DNA repair associated (BRCA1) anticorps
- breast cancer 1 (brca1) anticorps
- breast cancer 1, early onset (LOC755086) anticorps
- breast cancer 1, early onset (Brca1) anticorps
- BRCA1, DNA repair associated (Brca1) anticorps
- breast cancer 1, early onset (BRCA1) anticorps
- breast cancer 1 L homeolog (brca1.L) anticorps
- BRCA1 anticorps
- brcai anticorps
- brcc1 anticorps
- BROVCA1 anticorps
- iris anticorps
- LOC100224649 anticorps
- PNCA4 anticorps
- PPP1R53 anticorps
- pscp anticorps
- rnf53 anticorps
Protein level used designations for Breast Cancer 1 Protéines (BRCA1)
BRCA1/BRCA2-containing complex, subunit 1 , RING finger protein 53 , breast and ovarian cancer susceptibility protein 1 , breast and ovarian cancer sususceptibility protein 1 , breast cancer type 1 susceptibility protein , protein phosphatase 1, regulatory subunit 53 , BRCA1 homologue , breast cancer type 1 susceptibility protein homolog , breast cancer 1, early onset , BRCA1 homolog , breast and ovarian cancer susceptibility protein , breast cancer associated 1
GENE ID | SPECIES |
---|---|
672 | Homo sapiens |
353120 | Bos taurus |
373983 | Gallus gallus |
403437 | Canis lupus familiaris |
449497 | Pan troglodytes |
554178 | Monodelphis domestica |
712634 | Macaca mulatta |
733513 | Xenopus (Silurana) tropicalis |
755086 | Strongylocentrotus purpuratus |
100049662 | Sus scrofa |
100051990 | Equus caballus |
100224649 | Taeniopygia guttata |
100347269 | Oryctolagus cuniculus |
12189 | Mus musculus |
497672 | Rattus norvegicus |
493761 | Felis catus |
399391 | Xenopus laevis |