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anti-Human Cyclin B1 Anticorps:
anti-Mouse (Murine) Cyclin B1 Anticorps:
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Hamster Monoclonal Cyclin B1 Primary Antibody pour BI, FM - ABIN967426
Cao, Faha, Dembski, Tsai, Harlow, Dyson: Independent binding of the retinoblastoma protein and p107 to the transcription factor E2F. dans Nature 1992
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Human Polyclonal Cyclin B1 Primary Antibody pour WB - ABIN3043482
Ren, Huang, Xu, Yang, Yang, Hu: Isoflavone lupiwighteone induces cytotoxic, apoptotic, and antiangiogenic activities in DU-145 prostate cancer cells. dans Anti-cancer drugs 2015
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Human Polyclonal Cyclin B1 Primary Antibody pour FACS, IF (cc) - ABIN670296
Ghate, Chaudhuri, Sarkar, Sajem, Panja, Rout, Mandal: An antioxidant extract of tropical lichen, Parmotrema reticulatum, induces cell cycle arrest and apoptosis in breast carcinoma cell line MCF-7. dans PLoS ONE 2013
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Human Monoclonal Cyclin B1 Primary Antibody pour BI, FACS - ABIN967428
Dunphy, Brizuela, Beach, Newport: The Xenopus cdc2 protein is a component of MPF, a cytoplasmic regulator of mitosis. dans Cell 1988
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Human Polyclonal Cyclin B1 Primary Antibody pour DB, WB - ABIN1881155
Kreis, Sanhaji, Krämer, Sommer, Rödel, Strebhardt, Yuan: Restoration of the tumor suppressor p53 by downregulating cyclin B1 in human papillomavirus 16/18-infected cancer cells. dans Oncogene 2010
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Human Monoclonal Cyclin B1 Primary Antibody pour ICC, FACS - ABIN969006
Chou, Yen, Lee, Chen: Pro-apoptotic role of Cdc25A: activation of cyclin B1/Cdc2 by the Cdc25A C-terminal domain. dans The Journal of biological chemistry 2010
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Human Monoclonal Cyclin B1 Primary Antibody pour IHC, ELISA - ABIN969005
Okayama, Kumamoto, Saitou, Hayase, Kofunato, Sato, Miyamoto, Nakamura, Ohki, Sekikawa, Takenoshita: CD44v6, MMP-7 and nuclear Cdx2 are significant biomarkers for prediction of lymph node metastasis in primary gastric cancer. dans Oncology reports 2009
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Human Monoclonal Cyclin B1 Primary Antibody pour IHC, ELISA - ABIN965756
Mazure, Breton, Cancer, Mellado, Abilés, Avilés, Escarti, Ginés, Alvarez, Paez, Velasco, Pavón, Miras, Martínez Olmo, Culebras,: [Intragastric balloon in obesity treatment]. dans Nutrición hospitalaria : organo oficial de la Sociedad Española de Nutrición Parenteral y Enteral 2009
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Human Polyclonal Cyclin B1 Primary Antibody pour PLA, WB - ABIN514100
Liu, Chen, Chau, Jan, Chen, Hsu, Lin, Juang, Lu, Cheng, Chen, Chang, Ting, Kao, Hsiao, Huang: Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma. dans Molecular & cellular proteomics : MCP 2013
Human Polyclonal Cyclin B1 Primary Antibody pour FACS, IF (cc) - ABIN670303
Dai, Ye, Peng, Zhou, Bai, Xiao, Ma, Zhou, Tang, Yao, Cao, Qin, Liu, Tan: Aptamer TY04 inhibits the growth of multiple myeloma cells via cell cycle arrest. dans Tumour biology 2014
intestinal clock controls the expression of key cell cycle regulators, such as cdc2 (Montrer CDK1 Anticorps), wee1 (Montrer WEE1 Anticorps), p21 (Montrer CDKN1A Anticorps), PCNA (Montrer PCNA Anticorps) and cdk2 (Montrer CDK2 Anticorps), but only weakly influences cyclin B1, cyclin B2 (Montrer CCNB2 Anticorps) and cyclin E1 (Montrer CCNE1 Anticorps) expression.
the sequence in the coding region of cyclin B1 mRNA plays an important role as a cis (Montrer CISH Anticorps)-acting element in both subcellular localization and translational timing of mRNA
Reporter mRNAs with the whole cyclin B1 sequence precisely mimic the localization & translation of endogenous cyclin B1 mRNA. mRNAs containing cyclin B1 3' UTR (Montrer UTS2R Anticorps) but lacking ORFs had abnormal localization & precocious translational activation.
zebrafish cyclin B1 3'UTR (Montrer UTS2R Anticorps) was quantitatively less effective at stimulating polyadenylation and translation compared to the Xenopus cyclin B1 3'UTR (Montrer UTS2R Anticorps) during both zebrafish and Xenopus oocyte maturation
Data show that CDK1 (Montrer CDK1 Anticorps) and cyclin B synergize during oocyte maturation to inhibit Myt1 (Montrer PKMYT1 Anticorps) ensuring meiotic progression.
new role for Erk (Montrer MAPK1 Anticorps) in mitotic regulation, identification of the Ser (Montrer SIGLEC1 Anticorps) 101-directed kinase, and a picture of cyclin B1/Cdc2 regulation by the combinatorial action of distinct kinases
Cyclin B1 displays cytoskeleton-dependent localization in blastomere cortex during Xenopus embryonic cell cycle.
Cyclin B dissociation from CDK1 (Montrer CDK1 Anticorps) precedes cyclins B degradation upon CDK1 (Montrer CDK1 Anticorps) inactivation in mitotic embryo extracts and that proteasome proteolytic activity is dispensable for both activation and inactivation of CDK1 (Montrer CDK1 Anticorps) in such extracts.
We identified the known APC (Montrer APC Anticorps)/C regulator Cdh1 (Montrer CDH1 Anticorps) and the F-box protein (Montrer FBXW10 Anticorps) Fbxl15 (Montrer FBXL15 Anticorps) as specific modulators of N-cyclin B1-luciferase steady-state levels and turnover. Collectively, our studies suggest that analyzing the steady-state levels of luciferase fusion proteins in parallel facilitates identification of specific regulators of protein turnover.
Overexpression of cyclin B1 is correlated with poor survival in most solid tumors, which suggests that the expression status of cyclin B1 is a significant prognostic parameter in solid tumors. [review]
CDK9 (Montrer CDK9 Anticorps), in addition to CDK1 (Montrer CDK1 Anticorps), has roles in mediating the growth inhibitory effect of dinaciclib on cyclin B1 in triple negative breast cancer
Data show that Islet-1 (ISL1 (Montrer ISL1 Anticorps)) activated the expression of cyclin B1 (CCNB1), cyclin B2 (CCNB2 (Montrer CCNB2 Anticorps)) and c-myc (c-MYC (Montrer MYC Anticorps)) genes by binding to the conserved binding sites on their promoters or enhancers.
XIAP (Montrer XIAP Anticorps) is stable during mitotic arrest, but its function is controlled through phosphorylation by the mitotic kinase CDK1 (Montrer CDK1 Anticorps)-cyclin-B1 at S40.
ZIC5 (Montrer ZIC5 Anticorps) is highly upregulated in non-small cell lung cancer tumor tissues and may act as an oncogene (Montrer RAB1A Anticorps) by influencing CCNB1 and CDK1 (Montrer CDK1 Anticorps) complex expression
Knockdown of DRG2 (Montrer DRG2 Anticorps) elicited down-regulation of the major mitotic promoting factor, the cyclin B1/Cdk1 (Montrer CDK1 Anticorps) complex.
Mitochondrial Ribosomal Protein L10 regulates cyclin B1/Cdk1 (cyclin-dependent kinase 1 (Montrer CDK1 Anticorps)) activity and mitochondrial protein (Montrer COX6B2 Anticorps) synthesis in mammalian cells
Changes in expression and localization of cyclin B1 may constitute a part of the mechanism responsible for resistance of HL-60 cells to etoposide.
Data suggest that long non-coding RNA ZFAS1 may function as oncogene (Montrer RAB1A Anticorps) via destabilization of tumor suppressor protein p53 (p53 (Montrer TP53 Anticorps)) and through cyclin-dependent kinase 1 (CDK1 (Montrer CDK1 Anticorps))/cyclin B1 complex leading to cell cycle progression and inhibition of apoptosis.
Inhibition of CDK7 (Montrer CDK7 Anticorps) bypasses spindle assembly checkpoint via premature cyclin B degradation during oocyte meiosis.
timing of Ccnb1 mRNA translation in mouse oocytes is dependent on the presence of transcripts with different 3' untranslated regions
AURKA (Montrer AURKA Anticorps) induced phosphorylation and recruitment of CDC25B (Montrer CDC25B Anticorps) to MTOCs prior to p-Cyclin B1-Ser123, and this sequential regulation is essential for the commitment of the oocytes to resume meiosis.
that MAD2B may play an important role in high glucose-mediated podocyte injury of diabetic nephropathy via modulation of Cdh1, cyclin B1, and Skp2 expression
Parvovirus-induced depletion of cyclin B1 prevents mitotic entry of infected cells.
Cyclin B1/Cdk1 (Montrer CDK1 Anticorps)-mediated phosphorylation of mitochondrial substrates allows cells to sense and respond to increased energy demand for G2/M transition and, subsequently, to upregulate mitochondrial respiration for successful cell-cycle progression.
sticky siRNAs against survivin (Montrer BIRC5 Anticorps) and cyclin B1 efficiently blocks growth of established subcutaneaous B16-F10 (Montrer F10 Anticorps) tumors as well as formation and dissemination of melanoma lung metastases.
Inhibitions of Aurora B (Montrer AURKC Anticorps) and Cyclin-dependent kinase 1 (Montrer CDK1 Anticorps) activity in vertebrate cells also have opposite effects on the timing of abscission.
It was concluded that insensitivity of mouse germinal vesicle oocytes to cyclohexidine was due to the presence of sufficient cyclin B1, and that cyclin B1 level in such oocytes was maintained by an equilibrium between synthesis and degradation.
Data show nuclear accumulation of cyclin B1 with a subsequent premature increase in G2/M kinase activity in Nipa (Montrer ZC3HC1 Anticorps)-/- spermatocytes.
Cyclin B1 plays a significant role in promoting the maturation of large-follicle oocytes.
cyclin B1 distribution in porcine oocytes is affected by demecolcine-assisted enucleation
germinal vesicle is not required for the activation of M phase promoting factor during the first meiosis, but it is required for the second meiosis because of its promotion of CCNB1 accumulation
Results describe the expression of maternal cyclin B1 and Cdc2 (Montrer CDK1 Anticorps) during in vitro maturation of porcine oocytes.
Cyclin-dependent kinase (Montrer CDK1 Anticorps) inhibition did not affect the expression (mRNA and protein levels) and localization of maturation promoting factor(MPF (Montrer MSLN Anticorps)) and MAPK (Montrer MAPK1 Anticorps), and had nearly no effect on kinase activities during maturation.
link between cytoplasmic polyadenylation of cyclin B1 and translation/appearance of cyclin B1 protein before in vitro maturation of oocytes
Polyadenylation of cyclin B1 was also completely prevented when 3'-dA was added at 0 hr, and greatly reduced when added at 6 hr
The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites.
, cyclin B1
, cyclin B4
, G2/mitotic-specific cyclin B1
, cyclin B1, related sequence 1
, cyclin B1, related sequence 13
, cyclin B