SMAD2 ELISA Kit

Antigen Summary

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors. This protein can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin. Alternatively spliced transcript variants have been observed for this gene.

Alternative names and synonyms associated with SMAD2

• SMAD family member 2 (SMAD2) ELISA Kit
• SMAD family member 2-Z (SMAD2Z) ELISA Kit
• SMAD family member 2 (smad2) ELISA Kit
• SMAD family member 2 S homeolog (smad2.S) ELISA Kit
• SMAD family member 2 (Smad2) ELISA Kit

• JV18 ELISA Kit
• JV18-1 ELISA Kit
• MADH2 ELISA Kit
• MADR2 ELISA Kit
• hMAD-2 ELISA Kit
• Afficher tous les alias de synonymes
• hSMAD2 ELISA Kit
• jv18 ELISA Kit
• Xmad2 ELISA Kit
• madh2 ELISA Kit
• madr2 ELISA Kit
• XSmad2 ELISA Kit
• hmad-2 ELISA Kit
• hsmad2 ELISA Kit
• jv18-1 ELISA Kit
• smad-2 ELISA Kit
• fj43c06 ELISA Kit
• wu:fj43c06 ELISA Kit
• 7120426M23Rik ELISA Kit
• Madh2 ELISA Kit
• Madr2 ELISA Kit
• Smad-2 ELISA Kit
• mMad2 ELISA Kit
• MAD homolog 2 ELISA Kit
• Mothers against DPP homolog 2 ELISA Kit
• SMAD 2 ELISA Kit
• Smad2 ELISA Kit

Protein level used designations for SMAD2

MAD homolog 2 , SMAD, mothers against DPP homolog 2 , Sma- and Mad-related protein 2 , mother against DPP homolog 2 , mothers against decapentaplegic homolog 2 , SMAD 2 , mothers against DPP homolog 2 , mothers against decapentaplegic-like 2 , MAD (mothers against decapentaplegic, Drosophila) homolog 2 , SMA- and MAD-related protein 2 , SMAD family member 2 , Smad 2 , mad-related protein 2 , LOW QUALITY PROTEIN: mothers against decapentaplegic homolog 2