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Human TUBB Protein expressed in Escherichia coli (E. coli) - ABIN2127108
Liu, Deng, Yan, Cheng, Luo, Li, Yin, Qin: Novel Beta-Tubulin-Immobilized Nanoparticles Affinity Material for Screening β-Tubulin Inhibitors from a Complex Mixture. dans ACS applied materials & interfaces 2017
Human TUBB Protein expressed in HEK-293 Cells - ABIN2734558
Chang, Zhao, Wang, Chen, Yan: Screening citrullinated proteins in synovial tissues of rheumatoid arthritis using 2-dimensional western blotting. dans The Journal of rheumatology 2013
human tumor cells can acquire spontaneous mutations in beta1-tubulin that cause resistance to paclitaxel
Roles of tubulin beta 1,3 residues Ala428 and Thr429 in microtubule formation in vivo.
TUBB (Montrer TUBB2A Protéines) exon 4 mutations and mismatch repair defects do not play a significant role in paclitaxel/cisplatin resistance
Mutations in either TUBB (Montrer TUBB2A Protéines) or MAPRE2 (Montrer MAPRE2 Protéines) cause circumferential skin creases Kunze type.
the dipole moments of each tubulin isotype may influence their functional characteristics within the cell, resulting in differences for MT assembly kinetics and stability
Leucine point mutations viz. L215H, L217R, and L225M were reported for paclitaxel resistance in various cancers. In the current study, molecular mechanism of these resistance causing mutations in TUBB1 (Montrer TUBB1 Protéines) was explored using molecular docking, molecular dynamics simulation, binding energy estimation, free energy decomposition, principle component analysis and free energy landscape methods.
Data suggest a looser binding of the ligand in tubulin mutants.
Data show that tubulin phosphorylation and acetylation play important roles in the control of microtubule assembly and stability.
Data suggest that, while lacking a stable structure, NFL (Montrer NEFL Protéines)-TBS.40-63 peptide (a peptide derived from light neurofilament protein (Montrer NEFL Protéines)) preferentially binds on a specific single site located near C-terminal end of beta-tubulin.
Citrullination of TUBB (Montrer TUBB2A Protéines) is associated with neoplasms.
The axial elastic modulus of tubulin diminishes as the length of the monomer increases.
The results suggest that betaTub97EF upregulation at low temperature contributes to acclimation by stabilizing microtubules.
The model of molecular folding for the mRNP particle involving the mRNA of beta-tubulin 56D has been proposed.
Our results indicate that the maternally supplied beta1-Tubulin based microtubule network is sufficient for myoblast fusion, myotube elongation and sarcomere formation both during visceral and somatic muscle development in Drosophila embryogenesis
Codepletion of Vhl (Montrer VHL Protéines) with Mgr (Montrer GRHL1 Protéines) gives partial rescue of tubulin instability, monopolar spindle formation, and loss of centrosomes.
These data reveal that beta2-tubulin has robust properties for axoneme assembly, and that axonemal specializations are embedded in both the C-terminal tail and the body of the beta2 molecule.
Bagpipe (Montrer NKX3-1 Protéines) and Biniou serve as direct, partially redundant, and tissue-specific activators of the terminal differentiation gene beta 3Tub60D in the visceral mesoderm
Partially truncated beta2-tubulin (beta2Delta7) containing only the proximal portion of the C-terminal tail, including the axoneme motif, can support production of functional motile sperm.
beta2t plays an important role in salivary gland and myoblast migration
beta 5-tubulin\; polymerizes to form microtubules\; member of a family of structural proteins
, beta Ib tubulin
, beta-4 tubulin
, class I beta-tubulin
, tubulin beta chain
, tubulin beta polypeptide
, tubulin beta-1 chain
, tubulin beta-5 chain
, tubulin, beta polypeptide
, putative cobalt-zinc-cadmium outer membrane resistance protein
, Tubulin, Beta family member (tbb-6)
, tubb beta-5
, tubulin beta-1
, tubulin, beta, 5
, tubulin, beta 2A
, tubulin, beta class I
, tubulin beta-2B chain
, tubulin, beta 2B class IIb
, c(beta)7 tubulin
, tubulin beta 4'
, tubulin beta-7 chain
, tubulin, beta 2
, tubulin, beta 2A class IIa
, beta tubulin
, beta-1 tubulin
, beta-Tubulin at 56 D
, beta-tubulin 56D
, beta1 tubulin
, tubulin beta1-chain
, 60C beta tubulin
, b-3 tubulin
, b3 tubulin
, beta 3 tubulin
, beta-3 tubulin
, beta-Tubulin at 60A
, beta-tubulin 60D
, beta3 tubulin
, tubulin b-3
, b2 tubulin
, beta 2 tubulin
, beta2 tubulin
, testis-specific beta-tubulin
, beta4 tubulin
, tubulin, beta 5
, Class I beta-tubulin
, Tubulin beta-7 chain
, beta-tubulin isotype I
, class I beta tubulin