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Human Polyclonal ADCY9 Primary Antibody pour WB - ABIN2801902
Tantisira, Small, Litonjua, Weiss, Liggett: Molecular properties and pharmacogenetics of a polymorphism of adenylyl cyclase type 9 in asthma: interaction between beta-agonist and corticosteroid pathways. dans Human molecular genetics 2005
Show all 3 Pubmed References
Human Polyclonal ADCY9 Primary Antibody pour CM, ICC - ABIN2746180
Kolachala, Asamoah, Wang, Srinivasan, Merlin, Sitaraman: Interferon-gamma down-regulates adenosine 2b receptor-mediated signaling and short circuit current in the intestinal epithelia by inhibiting the expression of adenylate cyclase. dans The Journal of biological chemistry 2005
ADCY9 immunoreactivity score was significantly higher (P=0.002) in tumor tissues (6.40+/-1.26, n=200) than in adjacent normal samples (4.13+/-0.83, n=8). The IRS (Montrer IARS Anticorps) and mRNA expression of ADCY9 were correlated to colon cancer TNM (Montrer ODZ1 Anticorps) staging.
polymorphisms in the ADCY9 gene are significantly associated with asthma and/or allergy markers
The stronger TNF-alpha (Montrer TNF Anticorps) responses in young males compared to females may be partly associated with male-specific down-regulation of ADCY7 (Montrer Adcy7 Anticorps) and ADCY9.
The effects of dalcetrapib on atherosclerotic outcomes are determined by correlated polymorphisms in the ADCY9 gene.
The importance of miR (Montrer MLXIP Anticorps)-181a-mediated AC9 downregulation in acute promyelocytic leukemia (Montrer PML Anticorps), is reported.
Data indicate that adenylyl cyclase 9 (AC9) transcript is a direct target of miR (Montrer MLXIP Anticorps)-181b.
in heart, Yotiao (Montrer AKAP9 Anticorps) brings together PKA, PP1 (Montrer PPA1 Anticorps), PDE4D3, AC9, and the I(Ks) channel to achieve localized temporal regulation of beta-adrenergic stimulation.
The HIV-1 regulatory protein Tat (Montrer TAT Anticorps) was shown to inhibit the activity of adenylyl cyclase in rat microglial cells.
blocking glycosylation of AC9 significantly attenuates Galpha (Montrer SUCLG1 Anticorps)(s) stimulation.
in heart, Yotiao (Montrer AKAP9 Anticorps) brings together PKA, PP1 (Montrer PPP1CC Anticorps), PDE4D3, AC9, and the I(Ks) channel to achieve localized temporal regulation of beta-adrenergic stimulation.
miR (Montrer MLXIP Anticorps)-142-3p regulates the production of cAMP by targeting adenylyl cyclase (AC) 9 messenger RNA in CD4 (Montrer CD4 Anticorps)(+)CD25 (Montrer IL2RA Anticorps)(-) T cells and CD4 (Montrer CD4 Anticorps)(+)CD25 (Montrer IL2RA Anticorps)(+) T(REG (Montrer KCNH2 Anticorps)) cells.
Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. It is regulated by a family of G protein-coupled receptors, protein kinases, and calcium. The type 9 adenylyl cyclase is a widely distributed adenylyl cyclase, and it is stimulated by beta-adrenergic receptor activation but is insensitive to forskolin, calcium, and somatostatin.
ATP pyrophosphate-lyase 9
, adenylate cyclase type 9
, adenylate cyclase type IX
, adenylyl cyclase 9
, type IX ATP pyrophosphate-lyase
, adenylyl cyclase type 10
, adenylyl cyclase type IX
, adenylate cyclase 9
, adenylate cyclase type 9-like