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EPOR Produits

(Erythropoietin Receptor (EPOR))

Catégories

This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010].

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Catégories EPOR en vedette

EPOR Anticorps

High quality antibodies with extensive validation data.

EPOR Kits ELISA

Reliable ELISA kits for a wide range of species.

EPOR Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

EPOR recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IP
Validations
  • (6)
N° du produit ABIN560776
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (2)
  • (4)
N° du produit ABIN686347
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, FACS
Validations
  • (5)
N° du produit ABIN6243002
Quantité 400 μL
Fiche technique Fiche technique

EPOR recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
N° du produit ABIN6955646
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6955647
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN1979359
Quantité 96 tests
Fiche technique Fiche technique

EPOR recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7122817
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1352977
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1352979
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits EPOR

Vizcardo-Galindo, León-Velarde, Villafuerte: "High-Altitude Hypoxia Decreases Plasma Erythropoietin Soluble Receptor Concentration in Lowlanders." dans: High altitude medicine & biology, Vol. 21, Issue 1, pp. 92-98, (2020) (PubMed).

Tarantini, Valcarcel-Ares, Toth, Yabluchanskiy, Tucsek, Kiss, Hertelendy, Kinter, Ballabh, Süle, Farkas, Baur, Sinclair, Csiszar, Ungvari: "Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice." dans: Redox biology, Vol. 24, pp. 101192, (2019) (PubMed).

Chen, Li, Quan, Zhou, Zhao, Zhang, Hu, Hu: "The Effects of Curcumae Longae Radix, Curcuma phaeocaulis Radix and Their Processed Products on Epo/EpoR Pathway and CD62p." dans: Frontiers in pharmacology, Vol. 9, pp. 736, (2018) (PubMed).

Villafuerte, Corante, Anza-Ramírez, Figueroa-Mujíca, Vizcardo-Galindo, Mercado, Macarlupú, León-Velarde: "Plasma soluble erythropoietin receptor is decreased during sleep in Andean highlanders with Chronic Mountain Sickness." dans: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 121, Issue 1, pp. 53-8, (2016) (PubMed).

Li, Chen, Shao, Tang, Chen, Chen, Xu: "Oxidative stress induces the decline of brain EPO expression in aging rats." dans: Experimental gerontology, Vol. 83, pp. 89-93, (2016) (PubMed).

Zhong, Zhang: "Age-associated expression of erythropoietin and its receptor in rat spiral ganglion neurons and its association with neuronal apoptosis and hearing alterations." dans: Molecular medicine reports, Vol. 15, Issue 1, pp. 228-234, (2016) (PubMed).

Kai-lan, Si: "Pretreatment With Erythropoietin Attenuates Intestinal Ischemia Reperfusion Injury by Further Promoting PI3K/Akt Signaling Activation." dans: Transplantation proceedings, Vol. 47, Issue 6, pp. 1639-45, (2016) (PubMed).

Maxwell, Melendez-Rodríguez, Matchett, Aragones, Ben-Califa, Jaekel, Hengst, Lindner, Bernardini, Brockmeier, Fandrey, Grunert, Oster, Mittelman, El-Tanani, Thiersch, Schneider Gasser, Gassmann et al.: "Novel antibodies directed against the human erythropoietin receptor: creating a basis for clinical implementation. ..." dans: British journal of haematology, Vol. 168, Issue 3, pp. 429-42, (2015) (PubMed).

Hatayama, Ide: "Engineering of erythropoietin receptor for use as an affinity ligand." dans: Protein expression and purification, Vol. 111, pp. 1-8, (2015) (PubMed).

Villafuerte, Macarlupú, Anza-Ramírez, Corrales-Melgar, Vizcardo-Galindo, Corante, León-Velarde: "Decreased plasma soluble erythropoietin receptor in high-altitude excessive erythrocytosis and Chronic Mountain Sickness." dans: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 117, Issue 11, pp. 1356-62, (2014) (PubMed).

Synonymes et noms alternatifs relatifs à EPOR

erythropoietin receptor (EPOR), erythropoietin receptor (epor), erythropoietin receptor (Epor), erythropoietin receptor L homeolog (epor.L), EPO-R, EPOR, epor

Protein level used designations for EPOR

  • erythropoietin receptor
  • Erythropoietin receptor
  • type I single-transmembrane cytokine receptor
  • erythropoietin receptor-like
  • EPO-R
  • xlEPOR
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