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anti-Human LTBP2 Anticorps:
anti-Mouse (Murine) LTBP2 Anticorps:
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LTBP2 is a novel biomarker for the diagnosis of pancreatic cancer.
Our data suggest that LTBP2 acts as an oncogene (Montrer RAB1A Anticorps) in head and neck squamous cell carcinoma development and progression
knockdown of LTBP2 inhibits invasion and tumorigenesis in thyroid carcinoma cells.
We identified one nonsense mutation (c.2421G>A, p.W807X) in LTBP2 in eight Indian families. Among the mutations identified W807X in LTBP2 represent novel mutations.
LTBP-1 (Montrer LTBP1 Anticorps) and LTBP-2 are involved in the keratinization of oral epithelium.
The results showed that no deleterious mutations were found in coding regions of LTBP2 in patients with PCG, suggesting that it is not a causal gene for primary congenital glaucoma in the Han Chinese population.
LTBP-2 and FGF-2 (Montrer FGF2 Anticorps) are co-localized in fibrotic human keloid and hypertrophic scar.
LTBP-2 is a potent inhibitor of FGF-2 (Montrer FGF2 Anticorps) that may influence FGF-2 (Montrer FGF2 Anticorps) bioactivity during wound repair particularly in fibrotic tissues.
LTBP2 was able to reduce phosphorylation of p65 (Montrer GORASP1 Anticorps) at Serine 536, inhibit nuclear localization of active phosphorylated p65 (Montrer GORASP1 Anticorps), and impair the p65 (Montrer GORASP1 Anticorps) DNA-binding ability. This results in a consequential down-regulation of p65 (Montrer GORASP1 Anticorps)-related gene expression.
LTBP-2 is an essential component for the formation of microfibril bundles in ciliary zonules.
perlecan (Montrer HSPG2 Anticorps) HS was not essential for latent transforming growth factor-beta-1 (Montrer TGFB1 Anticorps) binding protein-2 deposition
Latent transforming growth factor beta-binding proteins-2 and -3 inhibit the proprotein convertase 5 (Montrer PCSK5 Anticorps)/6A.
These results suggest a novel regulatory mechanism of elastic fiber assembly in which LTBP-2 regulates targeting of DANCE on suitable microfibrils to form elastic fibers.
This is the first study to investigate the expression and localization of fibrillin proteins and latent TGF-beta (Montrer TGFB1 Anticorps) binding proteins affecting TGFbeta (Montrer TGFB1 Anticorps) bioavailability in the ovary.
The protein encoded by this gene belongs to the family of latent transforming growth factor (TGF)-beta binding proteins (LTBP), which are extracellular matrix proteins with multi-domain structure. This protein is the largest member of the LTBP family possessing unique regions and with most similarity to the fibrillins. It has thus been suggested that it may have multiple functions: as a member of the TGF-beta latent complex, as a structural component of microfibrils, and a role in cell adhesion.
latent transforming growth factor beta binding protein 2
, latent transforming growth factor beta binding protein 3
, latent transforming growth factor-beta binding protein 3
, latent-transforming growth factor beta-binding protein 2-like
, latent-transforming growth factor beta-binding protein 2
, LTBP-2 like protein
, latent-transforming growth factor beta-binding protein 3