BYL-719(Alpelisib)

Détails pour le produit réf. ABIN3219886
Application
Inhibition Assay (InhA), Functional Studies (Func)
Options
Fonction Alpelisib (BYL719) is a potent and selective PI3Kα inhibitor with IC50 of 5 nM in a cell-free assay, and minimal effect on PI3Kβ/γ/δ. Phase 2.
Attributs du produit Target: PI3K inhibitor
Receptor: PI3Kα
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Pureté 98 %
Formula C19H22F3N5O2S
Solubility DMSO > 10 mM
Sujet PI3K/Akt/mTOR Signaling
Poids moléculaire 441.47 g/mol
Numéro CAS 1217486-61-7
Indications d'application Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Stock -20 °C
Stockage commentaire For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Date de péremption 24 months