AZD2014

Détails pour le produit réf. ABIN3220161
Application
Inhibition Assay (InhA), Functional Studies (Func)
Options
Fonction AZD2014 is a novel mTOR inhibitor with IC50 of 2.8 nM in a cell-free assay, highly selective against multiple PI3K isoforms (α/β/γ/δ). Phase 2.
Attributs du produit Target: mTOR inhibitor,S6 Kinase inhibitor
Receptor: mTOR/P-Akt (S473)/pS6 (S235/236)
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Pureté 98 %
Formula C25H30N6O3
Solubility DMSO > 10 mM
Sujet PI3K/Akt/mTOR Signaling
Poids moléculaire 462.54 g/mol
Numéro CAS 1009298-59-2
Indications d'application Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Stock -20 °C
Stockage commentaire For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Date de péremption 24 months