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Binimetinib (MEK162, ARRY-162, ARRY-438162)

InhA, Func 606143-89-9
N° du produit ABIN3220235
  • Application
    Inhibition Assay (InhA), Functional Studies (Func)
    Fonction
    Binimetinib (MEK162, ARRY-162, ARRY-438162) is a potent inhibitor of MEK1/2 with IC50 of 12 nM in a cell-free assay. Phase 3.
    Attributs du produit
    Target: MEK inhibitor
    Receptor: MEK
    Purification
    All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
    Pureté
    100 %
    Formula
    C17H15BrF2N4O3
    Solubility
    200 mM in DMSO
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Solid
    Stock
    -20 °C
    Stockage commentaire
    For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
    Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
    Several freeze/thaw cycles should not damage the activity of our small molecule products.
    However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
    Date de péremption
    24 months
  • Sujet
    MAPK Signaling
    Poids moléculaire
    441.23 g/mol
    Numéro CAS
    606143-89-9
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