Binimetinib (MEK162, ARRY-162, ARRY-438162)

Détails pour le produit réf. ABIN3220235
Inhibition Assay (InhA), Functional Studies (Func)
Fonction Binimetinib (MEK162, ARRY-162, ARRY-438162) is a potent inhibitor of MEK1/2 with IC50 of 12 nM in a cell-free assay. Phase 3.
Attributs du produit Target: MEK inhibitor
Receptor: MEK
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Pureté 100 %
Formula C17H15BrF2N4O3
Solubility 200 mM in DMSO
Sujet MAPK Signaling
Poids moléculaire 441.23 g/mol
Numéro CAS 606143-89-9
Indications d'application Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Stock -20 °C
Stockage commentaire For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Date de péremption 24 months