Détails pour le produit réf. ABIN3220369
Inhibition Assay (InhA), Functional Studies (Func)
Fonction CHIR-98014 is a potent GSK-3α/β inhibitor with IC50 of 0.65 nM/0.58 nM in cell-free assays, with the ability to distinguish GSK-3 from its closest homologs Cdc2 and ERK2.
Attributs du produit Tradename: CHIR-98014
Target: GSK-3 inhibitor,S6 Kinase inhibitor,Src inhibitor,FGFR inhibitor
Receptor: GSK-3α/β,p70 S6K/c-Src/bFGFR
Status: Undetermined activity
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Pureté 99.04 %
Formula C20H17Cl2N9O2
Solubility DMSO 8 mg/mL,Water <1 mg/mL
Sujet Tyrosine Kinase/Adaptors,PI3K/Akt/mTOR Signaling
Poids moléculaire 486.31 g/mol
Numéro CAS 556813-39-9
Indications d'application Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Stock -20 °C
Stockage commentaire For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Date de péremption 24 months