Rociletinib (CO-1686, AVL-301)

Détails pour le produit réf. ABIN3220443
Application
Inhibition Assay (InhA), Functional Studies (Func)
Options
Fonction CO-1686 is a novel, irreversible and orally delivered kinase inhibitor that specifically targets the mutant forms of EGFR including T790M(IC50=21 nM).
Attributs du produit Target: EGFR inhibitor
Receptor: Mutant EGFR
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Pureté 99.30 %
Formula C27H28F3N7O3
Solubility DMSO > 10 mM
Sujet Tyrosine Kinase/Adaptors
Poids moléculaire 555.55 g/mol
Numéro CAS 1374640-70-6
Indications d'application Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Stock -20 °C
Stockage commentaire For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Date de péremption 24 months