Momelotinib (CYT387)

Détails pour le produit réf. ABIN3220478
Inhibition Assay (InhA), Functional Studies (Func)
Fonction CYT387(momelotinib) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, ~10-fold selectivity versus JAK3.
Attributs du produit Target: JAK inhibitor
Receptor: JAK1/JAK2/JAK3
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Pureté 98 %
Formula C23H22N6O2
Solubility DMSO ≥80mg/Ml
Sujet JAK/STAT Signaling
Poids moléculaire 414.46 g/mol
Numéro CAS 1056634-68-4
Indications d'application Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Stock -20 °C
Stockage commentaire For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Date de péremption 24 months