Dabrafenib (GSK2118436)

Détails pour le produit réf. ABIN3220487
Application
Inhibition Assay (InhA), Functional Studies (Func)
Options
Fonction Dabrafenib (GSK2118436) is a mutant BRAFV600 specific inhibitor with IC50 of 0.8 nM in cell-free assays, with 4- and 6-fold less potency against B-Raf(wt) and c-Raf, respectively.
Attributs du produit Target: Raf inhibitor
Receptor: B-raf, C-raf
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Pureté 98 %
Formula C23H20F3N5O2S2
Solubility Soluble in DMSO
Sujet MAPK Signaling
Poids moléculaire 519.56 g/mol
Numéro CAS 1195765-45-7
Indications d'application Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Stock -20 °C
Stockage commentaire For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Date de péremption 24 months