Dolutegravir (GSK1349572)

Détails pour le produit réf. ABIN3220585
Inhibition Assay (InhA), Functional Studies (Func)
Fonction Dolutegravir (GSK1349572) is a two-metal-binding HIV integrase inhibitor with IC50 of 2.7 nM in a cell-free assay, modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.
Attributs du produit Target: Integrase inhibitor
Receptor: HIV integrase
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Pureté 97 % +
Formula C20H18F2N3NaO5
Solubility 200 mM in DMSO
Sujet Microbiology & Virology,Proteases/Proteasome
Poids moléculaire 441.36 g/mol
Numéro CAS 1051375-19-9
Indications d'application Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Stock -20 °C
Stockage commentaire For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Date de péremption 24 months