EPZ011989

Détails pour le produit réf. ABIN3220655
Application
Inhibition Assay (InhA), Functional Studies (Func)
Options
Fonction EPZ011989 is a potent, selective orally bioavailable EZH2 inhibitor with Ki < 3 nM for EZH2 wt and EZH2 Y646, 15-fold selectivity over EZH1 and >3000-fold selectivity over other HMTase.
Attributs du produit Target: Histone Methyltransferase inhibitor
Receptor: EZH2
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Pureté 97 % +
Formula C35H51N5O4
Solubility 10 mM in DMSO
Sujet Chromatin/Epigenetic
Poids moléculaire 605.81 g/mol
Numéro CAS 1598383-40-4
Indications d'application Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Stock -20 °C
Stockage commentaire For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Date de péremption 24 months