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Rociletinib (CO-1686, AVL-301)

InhA, Func 1374640-70-6
N° du produit ABIN4877303
  • Application
    Inhibition Assay (InhA), Functional Studies (Func)
    Fonction
    CO-1686 is a novel, irreversible and orally delivered kinase inhibitor that specifically targets the mutant forms of EGFR including T790M(IC50=21 nM).
    Attributs du produit
    Target: EGFR inhibitor
    Receptor: Mutant EGFR
    Purification
    All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
    Pureté
    99.30 %
    Formula
    C27H28F3N7O3
    Solubility
    DMSO > 10 mM
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Solid
    Stock
    -20 °C
    Stockage commentaire
    For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
    Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
    Several freeze/thaw cycles should not damage the activity of our small molecule products.
    However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
    Date de péremption
    24 months
  • Sujet
    Tyrosine Kinase/Adaptors
    Poids moléculaire
    555.55 g/mol
    Numéro CAS
    1374640-70-6
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