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Baricitinib (LY3009104, INCB028050)

InhA, Func 1187594-09-7
N° du produit ABIN4877699
  • Application
    Inhibition Assay (InhA), Functional Studies (Func)
    Fonction
    Baricitinib (LY3009104, INCB028050) is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM in cell-free assays, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2. Phase 3.
    Attributs du produit
    Target: JAK inhibitor
    Receptor: JAK1,JAK2,TYK2,JAK3
    Purification
    All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
    Pureté
    100 %
    Formula
    C16H17N7O2S
    Solubility
    Soluble in DMSO
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Solid
    Stock
    -20 °C
    Stockage commentaire
    For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
    Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
    Several freeze/thaw cycles should not damage the activity of our small molecule products.
    However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
    Date de péremption
    24 months
  • Sujet
    JAK/STAT Signaling
    Poids moléculaire
    371.42 g/mol
    Numéro CAS
    1187594-09-7
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