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Momelotinib (CYT387)

InhA, Func 1056634-68-4
N° du produit ABIN5678087
  • Application
    Inhibition Assay (InhA), Functional Studies (Func)
    Fonction
    CYT387(momelotinib) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, ~10-fold selectivity versus JAK3.
    Attributs du produit
    Target: JAK inhibitor
    Receptor: JAK1/JAK2/JAK3
    Purification
    All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
    Pureté
    98 %
    Formula
    C23H22N6O2
    Solubility
    DMSO ≥80mg/Ml
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Solid
    Stock
    -20 °C
    Stockage commentaire
    For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
    Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
    Several freeze/thaw cycles should not damage the activity of our small molecule products.
    However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
    Date de péremption
    24 months
  • Sujet
    JAK/STAT Signaling
    Poids moléculaire
    414.46 g/mol
    Numéro CAS
    1056634-68-4
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