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Dolutegravir (GSK1349572)

InhA, Func 1051375-19-9
N° du produit ABIN4877153
  • Application
    Inhibition Assay (InhA), Functional Studies (Func)
    Fonction
    Dolutegravir (GSK1349572) is a two-metal-binding HIV integrase inhibitor with IC50 of 2.7 nM in a cell-free assay, modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.
    Attributs du produit
    Target: Integrase inhibitor
    Receptor: HIV integrase
    Purification
    All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
    Pureté
    97 % +
    Formula
    C20H18F2N3NaO5
    Solubility
    200 mM in DMSO
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Solid
    Stock
    -20 °C
    Stockage commentaire
    For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
    Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
    Several freeze/thaw cycles should not damage the activity of our small molecule products.
    However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
    Date de péremption
    24 months
  • Sujet
    Microbiology & Virology,Proteases/Proteasome
    Poids moléculaire
    441.36 g/mol
    Numéro CAS
    1051375-19-9
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