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BIX02189

InhA, Func 1094614-85-3
N° du produit ABIN5678854
  • Application
    Inhibition Assay (InhA), Functional Studies (Func)
    Fonction
    BIX02189 is a selective inhibitor of MEK5 with IC50 of 1.5 nM, also inhibits ERK5 catalytic activity with IC50 of 59 nM in cell-free assays, and does not inhibit closely related kinases MEK1, MEK2, ERK2, and JNK2.
    Attributs du produit
    Target: MEK inhibitor
    Receptor: MEK5/ERK5/TGFβ/MEK1/ERK1/JNK1/EGFR/STK16
    Purification
    All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
    Pureté
    97 % +
    Formula
    C27H28N4O2
    Solubility
    100 mM in DMSO
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Solid
    Stock
    -20 °C
    Stockage commentaire
    For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
    Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
    Several freeze/thaw cycles should not damage the activity of our small molecule products.
    However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
    Date de péremption
    24 months
  • Sujet
    MAPK Signaling
    Poids moléculaire
    440.54 g/mol
    Numéro CAS
    1094614-85-3
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