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anti-Human Prohibitin 2 Anticorps:
anti-Mouse (Murine) Prohibitin 2 Anticorps:
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Human Polyclonal Prohibitin 2 Primary Antibody pour ICC, IF - ABIN151315
He, Feng, Mukherjee, Lonard, DeMayo, Katzenellenbogen, Lydon, OMalley: A repressive role for prohibitin in estrogen signaling. dans Molecular endocrinology (Baltimore, Md.) 2008
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Human Polyclonal Prohibitin 2 Primary Antibody pour IP, WB - ABIN151317
Heidler, Al-Furoukh, Kukat, Salwig, Ingelmann, Seibel, Krüger, Holtz, Wittig, Braun, Szibor: Nitric oxide-associated protein 1 (NOA1) is necessary for oxygen-dependent regulation of mitochondrial respiratory complexes. dans The Journal of biological chemistry 2011
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the present study suggested that PHB2 may promote Prostate cancer cell migration by inhibiting the expression of AKT2 (Montrer AKT2 Anticorps). These results provide information regarding the role of PHB2 in Prostate cancer migration and malignancy
Taken together, the results indicate that PHB2 plays a central role in p21 (Montrer CDKN1A Anticorps) upregulation following GGCT (Montrer GGCT Anticorps) knockdown and as such may promote deregulated proliferation of cancer cells by suppressing p21 (Montrer CDKN1A Anticorps).
analysis of LGALS3, PHB2, MUC1, and GK2 expression with CA15-3 in early-stage breast cancer
Fluorizoline bind to prohibitin (Montrer PHB Anticorps), inducing mitochondrial apoptotic pathway through NOXA (Montrer PMAIP1 Anticorps) and BIM (Montrer BCL2L11 Anticorps) upregulation.
REA modulates cross talk among multiple cell types in the uterine tissue and host background, serving as a brake on the estradiol-ER axis and restraining multiple aspects that contribute to the pathologic progression of endometriosis.
BIG3 (Montrer WDR5 Anticorps) may block the KPNAs (KPNA1 (Montrer KPNA1 Anticorps), KPNA5 (Montrer KPNA5 Anticorps), and KPNA6 (Montrer KPNA6 Anticorps)) binding region(s) of PHB2.
results show that PHB2 binds to the ligand binding domain of ERalpha (Montrer ESR1 Anticorps) with a conformational change in the helix 12 of ERalpha (Montrer ESR1 Anticorps)
Functional analysis of selected regulated proteins revealed that knockdown of HNRPD (Montrer HNRNPD Anticorps), PHB2 and UB2V2 (Montrer UBE2V2 Anticorps) can increase HCMV replication, while knockdown of A4 and KSRP (Montrer KHSRP Anticorps) resulted in decreased HCMV replication.
These results demonstrate that estradiol upregulates REA expression and recruits REA via ERalpha (Montrer ESR1 Anticorps) to the EREs on the RORgammaT promoter region, thus inhibiting RORgammaT expression and Th17 differentiation.
BIG3 (ARFGEF3) is predicted to interact with its partner PHB2 through an ARM-type alpha-helical structure.
CARL can suppress mitochondrial fission and apoptosis by targeting miR (Montrer MLXIP Anticorps)-539 and PHB2.
results suggest that PHB2 is a crucial mitochondrial regulator for homeostasis and lineage-specific differentiation of ES cells.
Loss of PHB2 impairs the stability of OPA1 (Montrer MED12 Anticorps), affects mitochondrial ultrastructure, and induces the perinuclear clustering of mitochondria in hippocampal neurons
REA physiologically restrains endometrial stromal cell decidualization, controlling the timing and magnitude of decidualization to coordinate uterine differentiation with concurrent embryo development that is essential for implantation and fertility.
PHB1 (Montrer PHB Anticorps) and PHB2 are critical mediators in promoting 3T3-L1 adipocyte differentiation and may be the potential targets for obesity therapies
Optimal uterine development and functional activities require the normal gene dosage of REA, with partial or complete deletion resulting in hyperresponsiveness or underresponsiveness to hormone and subfertility or infertility, respectively.
Serine phosphorylation of PHB2 by CaMK IV (Montrer CAMK4 Anticorps) relieves its inhibition on MEF2 (Montrer MEF2C Anticorps).
Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging (By similarity).
B-cell receptor-associated protein 37
, prohibitin 2
, B-cell associated protein
, B-cell receptor-associated protein BAP37
, repressor of estrogen receptor activity
, B-cell receptor associated protein 37