FNDC5 Kit ELISA

N° du produit ABIN2745465

Détail du produit FNDC5 Kit ELISA

Antigène: FNDC5 (Fibronectin Type III Domain Containing 5 (FNDC5))

Reactivité: Humain, Souris, Rat, Singe

Méthode de détection: Colorimetric

Type de méthode: Competition ELISA

Gamme de detection: 0.001-5 μg/mL

Seuil minimal de détection: 0.001 μg/mL

Application: ELISA

Type d'échantillon: Cell Culture Supernatant, Plasma, Serum

Analytical Method: Quantitative

Specificité: Detects human irisin. It should also work in mouse, rat and monkey biological samples.

Réactivité croisée: Humain, Singe, Souris, Rat (Rattus)

Aucune reactivité croisée: Souris

Réactivité croisée (Details): Does not cross-react with FNDC4, human adiponectin, human Nampt, human RBP4, human clusterin, human leptin, human vaspin, human GPX3, human resistin, human ACE2, human lipocalin-2, human ANGPTL3, human ANGPTL6, human DNER, human DLK1, human calreticulin, human IL-33, mouse Nampt, mouse clusterin, mouse vaspin or mouse resistin.

Sensibilité: 1 ng/mL

Attributs du produit: Irisin Competitive ELISA Kit (Twin Plex)

Information d'application

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: 4 °C

Stockage commentaire: Short Term Storage: +4°C
Long Term Storage: +4°C
12 months after the day of manufacturing. See expiry date on ELISA Kit box.

Détail du antigène

Antigène: FNDC5 (Fibronectin Type III Domain Containing 5 (FNDC5))

Autre désignation: Irisin (FNDC5 Produits)

Synonymes: FRCP2 Kit ELISA, irisin Kit ELISA, 1500001L03Rik Kit ELISA, AI836596 Kit ELISA, C87088 Kit ELISA, PeP Kit ELISA, Pxp Kit ELISA, fndc5 Kit ELISA, si:dkey-264p5.1 Kit ELISA, zgc:158684 Kit ELISA, fibronectin type III domain containing 5 Kit ELISA, fibronectin type III domain containing 5b Kit ELISA, FNDC5 Kit ELISA, Fndc5 Kit ELISA, fndc5b Kit ELISA

Sujet: Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone Irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure. Circulating irisin levels were shown to be upregulated after acute exercise. Increase of irisin under conditions of obesity may indicate a physiological function to improve glucose tolerance.

UniProt: Q8NAU1

Pathways: Hormone Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation