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ACVRL1 Kit ELISA

ACVRL1 Reactivité: Humain AA 22-118 Colorimetric Sandwich ELISA
N° du produit ABIN5510685
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    ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))
    Épitope
    AA 22-118
    Reactivité
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Méthode de détection
    Colorimetric
    Type de méthode
    Sandwich ELISA
    Application
    ELISA
    Fonction
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human ALK-1/ACVRL1
    Marque
    PicoKine™
    Analytical Method
    Quantitative
    Specificité
    Expression system for standard: NSO
    Immunogen sequence: D22-Q118
    Réactivité croisée (Details)
    There is no detectable cross-reactivity with other relevant proteins.
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  • Plaque
    Pre-coated
    Restrictions
    For Research Use only
  • Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    Date de péremption
    12 months
  • Antigène Voir toutes ACVRL1 Kits ELISA
    ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))
    Autre désignation
    ACVRL1 (ACVRL1 Produits)
    Synonymes
    ACVRL1 Kit ELISA, vgb Kit ELISA, alk1 Kit ELISA, zehn1109 Kit ELISA, hm:zehn1109 Kit ELISA, ACVRLK1 Kit ELISA, ALK-1 Kit ELISA, ALK1 Kit ELISA, HHT Kit ELISA, HHT2 Kit ELISA, ORW2 Kit ELISA, SKR3 Kit ELISA, TSR-I Kit ELISA, R-3 Kit ELISA, R3 Kit ELISA, SETHKIR Kit ELISA, AI115505 Kit ELISA, AI427544 Kit ELISA, Acvrlk1 Kit ELISA, Alk1 Kit ELISA, activin A receptor like type 1 Kit ELISA, activin A receptor type II-like 1 Kit ELISA, activin A receptor, type II-like 1 Kit ELISA, ACVRL1 Kit ELISA, acvrl1 Kit ELISA, Acvrl1 Kit ELISA
    Sujet

    Protein Function: Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well. .

    Background: Serine/threonine-protein kinase receptor R3 is an enzyme that in humans is encoded by the ACVRL1 gene. It is also known as activin receptor-like kinase 1, or ALK1. This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.

    Synonyms: Serine/threonine-protein kinase receptor R3,SKR3,2.7.11.30,Activin receptor-like kinase 1,ALK-1,TGF-B superfamily receptor type I,TSR-I,ACVRL1,ACVRLK1, ALK1,

    Full Gene Name: Serine/threonine-protein kinase receptor R3

    Cellular Localisation: Cell membrane, Single-pass type I membrane protein.
    UniProt
    P37023
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